Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.64 |
| ▸ | RAB9A | P51151 | 2/20 | 0.64 |
| ▸ | HPGD | P15428 | 1/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 4/20 | 0.49 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | STS | P08842 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | ESRRA | P11474 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25960673 | 0.93 | RAB9A (0.56) | MAPTRAB9AHPGDNPSR1SMN1; SMN2 | |
| SCHEMBL25908089 | 0.86 | PTGS2 (0.59) | MAPTRAB9AHPGDSMN1; SMN2LMNA | |
| SCHEMBL25908092 | 0.86 | MAPT (0.51) | MAPTRAB9AHPGDSMN1; SMN2MAOB | |
| SCHEMBL10588626 | 0.84 | MAPT (0.62) | MAPTRAB9AHPGDNPSR1SMN1; SMN2 | |
| SCHEMBL1682171 | 0.84 | HTT (0.68) | MAPTRAB9AHPGDPARP10L3MBTL1 | |
| SCHEMBL4743129 | 0.84 | MAPT (0.62) | MAPTRAB9AHPGDNPSR1SMN1; SMN2 | |
| SCHEMBL5608673 | 0.84 | HPGD (0.62) | MAPTRAB9AHPGDSMN1; SMN2MAOB | |
| SCHEMBL9422294 | 0.83 | SRD5A2 (0.61) | HPGDPARP10 | |
| SCHEMBL11509042 | 0.82 | MAPT (0.60) | MAPTRAB9AHPGDNPSR1SMN1; SMN2 | |
| SCHEMBL13679391 | 0.82 | RAB9A (0.60) | MAPTRAB9AHPGDNPSR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0410929-A2 | Linear polymers | CIBA-GEIGY AG (CH) | 1991-01-30 | — | — | EP | disclosed |