Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.58 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.58 |
| ▸ | NPC1 | O15118 | 4/20 | 0.52 |
| ▸ | RAB9A | P51151 | 4/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9396568 | 0.89 | HDAC6 (0.72) | HDAC6HDAC1HDAC8NPC1RAB9A | |
| SCHEMBL18893845 | 0.89 | NPC1 (0.68) | HDAC6HDAC1HDAC8NPC1RAB9A | |
| SCHEMBL18893797 | 0.89 | TP53 (0.55) | HDAC6HDAC1HDAC8NPC1RAB9A | |
| SCHEMBL28784675 | 0.78 | HDAC6 (0.72) | HDAC6HDAC1HDAC8NPC1RAB9A | |
| SCHEMBL26690726 | 0.78 | HDAC6 (0.44) | HDAC6HDAC1HDAC8NPC1RAB9A | |
| SCHEMBL19075478 | 0.77 | TSHR (0.57) | HDAC6HDAC1HDAC8NPC1RAB9A | |
| SCHEMBL11902286 | 0.77 | HDAC1 (0.54) | HDAC6HDAC1HDAC8NPC1RAB9A | |
| SCHEMBL8343925 | 0.77 | NOTUM (0.54) | HDAC6HDAC1HDAC8NPC1RAB9A | |
| SCHEMBL11509023 | 0.77 | ALDH1A1 (0.48) | HDAC6HDAC1HDAC8NPC1RAB9A | |
| SCHEMBL3107804 | 0.76 | RAB9A (0.55) | HDAC6HDAC1HDAC8NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4069332-A | 5,5'-PHENYLENEBIS(1,2,4-OXADIAZOLE-3-CARBOXYLIC ACIDS OR ESTERS) | THE UPJOHN COMPANY (US) | 1978-01-17 | — | — | US | claimed |
| US-4159336-A | ANTIALLERGENS | THE UPJOHN COMPANY (US) | 1979-06-26 | — | — | US | disclosed |
| US-4069332-A | 5,5'-PHENYLENEBIS(1,2,4-OXADIAZOLE-3-CARBOXYLIC ACIDS OR ESTERS) | THE UPJOHN COMPANY (US) | 1978-01-17 | — | — | US | disclosed |