Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD40 | P25942 | 2/20 | 0.69 |
| ▸ | CD40LG | P29965 | 2/20 | 0.69 |
| ▸ | RAB9A | P51151 | 4/20 | 0.58 |
| ▸ | KDR | P35968 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.56 |
| ▸ | MEN1 | O00255 | 6/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.53 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | CASP3 | P42574 | 1/20 | 0.53 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.51 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.51 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11439477 | 0.89 | CD40 (0.56) | CD40CD40LGRAB9AKDRNPC1 | |
| SCHEMBL11431874 | 0.89 | CD40 (0.56) | CD40CD40LGRAB9AKDRNPC1 | |
| SCHEMBL11439166 | 0.89 | CD40 (0.58) | CD40CD40LGRAB9AKDRNPC1 | |
| SCHEMBL11762076 | 0.85 | KMT2A (0.60) | CD40CD40LGRAB9AKDRNPC1 | |
| SCHEMBL19021224 | 0.85 | CD40 (0.92) | CD40CD40LGRAB9AKDRNPC1 | |
| SCHEMBL11425328 | 0.84 | RAB9A (0.61) | CD40CD40LGRAB9AKDRNPC1 | |
| SCHEMBL11437141 | 0.84 | RAB9A (0.61) | CD40CD40LGRAB9AKDRNPC1 | |
| SCHEMBL11422168 | 0.84 | RAB9A (0.55) | CD40CD40LGRAB9AKDRNPC1 | |
| SCHEMBL11430290 | 0.83 | KMT2A (0.63) | CD40CD40LGRAB9AKDRNPC1 | |
| SCHEMBL11473094 | 0.83 | APEX1 (0.54) | CD40CD40LGRAB9AKDRNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4180587-A | Ureylene phenylene anionic naphthalenesulfonic acids as complement inhibitors | AMERICAN CYANAMID COMPANY (US) | 1979-12-25 | — | — | US | disclosed |