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SCHEMBL11511754

SCHEMBL11511754

C=C(C)C(=O)OCC[SiH2]OC(OCCCC)OCCCC

nearest known ligand 0.51

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ TSHR P16473 4/20 0.51
▸ THRB P10828 1/20 0.41
▸ POLB P06746 1/20 0.38
▸ APEX1 P27695 1/20 0.38
▸ HTT P42858 1/20 0.38
▸ TDP1 Q9NUW8 1/20 0.38
▸ ALDH1A1 P00352 3/20 0.36
▸ HPGD P15428 1/20 0.33
▸ ATM Q13315 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6928065 0.93 TSHR (0.54) TSHRTHRBPOLBAPEX1HTT
SCHEMBL22115838 0.91 TSHR (0.59) TSHRTHRBPOLBAPEX1HTT
SCHEMBL22115830 0.83 TSHR (0.56) TSHRTHRBPOLBAPEX1HTT
SCHEMBL20555058 0.81 TSHR (0.49) TSHRTHRBPOLBAPEX1HTT
SCHEMBL4753656 0.80 TSHR (0.44) TSHRTHRBPOLBAPEX1HTT
SCHEMBL22115857 0.79 TSHR (0.54) TSHRTHRBPOLBAPEX1HTT
SCHEMBL14893 0.76 TSHR (0.84) TSHRTHRBPOLBAPEX1HTT
SCHEMBL19066401 0.76 TSHR (0.84) TSHRTHRBPOLBAPEX1HTT
SCHEMBL11583525 0.76 TSHR (0.84) TSHRTHRBPOLBAPEX1HTT
SCHEMBL140539 0.75 TSHR (0.57) TSHRTHRBPOLBAPEX1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4133938-A ACRYLOYLOXYALKYLALKOXYSILANE-ACRYLATE REACTION PRODUCT, MASONRY SWS SILICONES CORPORATION (US) 1979-01-09 — — US disclosed