Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 3/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.31 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22115838 | 0.95 | TSHR (0.59) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL11511754 | 0.93 | TSHR (0.51) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL20555058 | 0.89 | TSHR (0.49) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL22115830 | 0.88 | TSHR (0.56) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL4753656 | 0.87 | TSHR (0.44) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL22115857 | 0.83 | TSHR (0.54) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL1017355 | 0.81 | TSHR (0.62) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL22115824 | 0.81 | TSHR (0.61) | TSHRTHRBALDH1A1HPGDATM | |
| SCHEMBL140539 | 0.80 | TSHR (0.57) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL28374752 | 0.80 | TSHR (0.45) | TSHRTHRBPOLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6518364-B2 | Subjecting mixture of monomer(s), water, surfactant, free radical source and a control agent to polymerization | SYMYX TECHNOLOGIES, INC. | 2003-02-11 | — | — | US | disclosed |