SCHEMBL140539

SCHEMBL140539

C=C(C)C(=O)OCCC[SiH2]C(OCCCC)OCCCC

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.57
THRB P10828 1/20 0.42
TDP1 Q9NUW8 2/20 0.42
POLB P06746 1/20 0.42
APEX1 P27695 1/20 0.42
HTT P42858 1/20 0.42
ALDH1A1 P00352 3/20 0.41
HPGD P15428 2/20 0.37
ATM Q13315 1/20 0.35
LMNA P02545 2/20 0.33
CYP1A2 P05177 2/20 0.33
CYP2C19 P33261 2/20 0.33
ESR1 P03372 1/20 0.33
CYP2D6 P10635 1/20 0.33
MAPK1 P28482 1/20 0.33
NR1H2 P55055 1/20 0.33
RNASEL Q05823 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
RECQL P46063 1/20 0.32
CYP3A4 P08684 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29022840 0.97 TSHR (0.54) TSHRTHRBTDP1POLBAPEX1
SCHEMBL22115820 0.94 TSHR (0.62) TSHRTHRBTDP1POLBAPEX1
SCHEMBL137795 0.89 TSHR (0.53) TSHRTHRBTDP1POLBAPEX1
SCHEMBL22115856 0.87 TSHR (0.59) TSHRTHRBTDP1POLBAPEX1
SCHEMBL28515660 0.86 TSHR (0.54) TSHRTHRBTDP1POLBAPEX1
SCHEMBL3917258 0.85 TSHR (0.45) TSHRTHRBTDP1POLBAPEX1
SCHEMBL876650 0.85 TSHR (0.56) TSHRTHRBTDP1POLBAPEX1
SCHEMBL21066734 0.84 TSHR (0.58) TSHRTHRBTDP1POLBAPEX1
SCHEMBL16537548 0.84 TSHR (0.58) TSHRTHRBTDP1POLBAPEX1
SCHEMBL27511005 0.84 TSHR (0.58) TSHRTHRBTDP1POLBAPEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 778 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025084741-A1 POLYOLEFIN GRAFT COPOLYMER PRODUCED USING INITIATOR CONTAINING AZIDOFORMATE GROUP AND PRODUCTION METHOD THEREFOR 세종대학교산학협력단 2025-04-24 WO claimed
CN-112533910-B Monoethylenically unsaturated monomers and their use 博斯蒂克股份公司 2024-05-10 CN claimed
US-11834429-B2 Monoethylenically unsaturated monomers and uses thereof BOSTIK SA (FR) 2023-12-05 US claimed
US-20210179576-A1 MONOETHYLENICALLY UNSATURATED MONOMERS AND USES THEREOF UNIVERSITE DE RENNES (FR) 2021-06-17 US claimed
CN-112533910-A Monoethylenically unsaturated monomers and their use 博斯蒂克股份公司 2021-03-19 CN claimed
EP-1675880-B1 METHOD FOR PARTIAL OR TOTAL OXIDATION OF ONE OR SEVERAL THIOCARBONYLTHIO ENDS OF A POLYMER OBTAINED BY RADICAL POLYMERISATION CONTROLLED BY REVERSIBLE ADDITION-CLEAVAGE RHODIA CHIMIE SA (FR) 2019-03-13 EP claimed
US-20170298026-A1 ALL PURPOSE RAFT AGENT COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2017-10-19 US claimed
EP-3204353-A1 ALL PURPOSE RAFT AGENT Commonwealth Scientific and Industrial Research Organisation (AU) 2017-08-16 EP claimed
US-20160340463-A1 PROCESS FOR PREPARING A POLYMER NEWSOUTH INNOVATIONS PTY LIMITED (AU) 2016-11-24 US claimed
WO-2016054689-A1 ALL PURPOSE RAFT AGENT COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2016-04-14 WO claimed
EP-1149075-A1 SYNTHESIS OF DITHIOESTER CHAIN TRANSFER AGENTS AND USE OF BIS(THIOACYL) DISULFIDES OR DITHIOESTERS AS CHAIN TRANSFER AGENTS E.I. DU PONT DE NEMOURS AND COMPANY (US) 2001-10-31 EP claimed
US-6291620-B1 Polymer synthesis E. I. DU PONT DE NEMOURS AND COMPANY 2001-09-18 US claimed
EP-0791016-B1 POLYMER SYNTHESIS DU PONT (US) 2000-07-12 EP claimed
WO-2000035960-A2 OLIGOMERIZATION, POLYMERIZATION AND COPOLYMERIZATION OF SUBSTITUTED AND UNSUBSTITUTED α-METHYLENE-η-BUTYROLACTONES AND PRODUCTS THEREOF E.I. DU PONT DE NEMOURS AND COMPANY (US) 2000-06-22 WO claimed
EP-1003793-A1 FUNCTIONALIZED DIENE OLIGOMERS E.I. DU PONT DE NEMOURS AND COMPANY (US) 2000-05-31 EP claimed
WO-1999009077-A1 FUNCTIONALIZED DIENE OLIGOMERS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1999-02-25 WO claimed
WO-1999005099-A1 SYNTHESIS OF DITHIOESTER CHAIN TRANSFER AGENTS AND USE OF BIS(THIOACYL) DISULFIDES OR DITHIOESTERS AS CHAIN TRANSFER AGENTS COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 1999-02-04 WO claimed
US-5847060-A Functionalized diene oligomers E. I. DU PONT DE NEMOURS AND COMPANY (US) 1998-12-08 US claimed
EP-0791016-A1 POLYMER SYNTHESIS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1997-08-27 EP claimed
WO-1996015157-A1 POLYMER SYNTHESIS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1996-05-23 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11834429-B2 Monoethylenically unsaturated monomers and uses thereof MEP1A, MEP1B, ALOX5 TSHR 4885/4885THRB 4861/4885TDP1 3660/4885
US-20170298026-A1 ALL PURPOSE RAFT AGENT NPC1L1, RFTN1, SGMS2 TSHR 4058/4885THRB 4068/4885TDP1 3736/4885
US-20210179576-A1 MONOETHYLENICALLY UNSATURATED MONOMERS AND USES THEREOF MEP1A, MEP1B, ALOX5 TSHR 4885/4885THRB 4861/4885TDP1 3660/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.