Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 2/20 | 0.47 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.47 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.47 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.47 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.46 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.46 |
| ▸ | APP | P05067 | 4/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2728744 | 0.83 | TSHR (0.53) | — | |
| SCHEMBL490900 | 0.82 | CA12 (0.54) | ESR1 | |
| SCHEMBL5668367 | 0.81 | TSHR (0.51) | — | |
| SCHEMBL27451188 | 0.80 | NR5A1 (0.51) | ESR1 | |
| SCHEMBL27861042 | 0.80 | NR5A1 (0.51) | ESR1 | |
| SCHEMBL490879 | 0.79 | LMNA (0.52) | NAAA | |
| Butane SCHEMBL28029368 | 0.78 | TSHR (0.50) | ESR1 | |
| SCHEMBL1263817 | 0.78 | ESR1 (0.39) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL11255781 | 0.78 | TSHR (0.47) | — | |
| SCHEMBL424035 | 0.77 | ESR1 (0.41) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4144224-A | FOR POLYOLEFINS, POLYAMIDES, AND POLYURETHANES | CIBA-GEIGY CORPORATION (US) | 1979-03-13 | — | — | US | disclosed |