Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2728744 | 0.98 | TSHR (0.53) | TSHRTP53CYP3A4MAPK1ALDH1A1 | |
| SCHEMBL10825007 | 0.95 | TSHR (0.50) | TSHRTP53CYP3A4MAPK1ALDH1A1 | |
| SCHEMBL31074064 | 0.82 | TSHR (0.53) | TSHRALDH1A1LMNATDP1POLB | |
| SCHEMBL10858287 | 0.82 | TSHR (0.53) | TSHRALDH1A1LMNATDP1POLB | |
| SCHEMBL6726998 | 0.81 | TSHR (0.51) | TSHRTP53CYP3A4MAPK1ALDH1A1 | |
| SCHEMBL11512129 | 0.81 | NAAA (0.47) | — | |
| SCHEMBL27679038 | 0.80 | TSHR (0.49) | TSHRTP53CYP3A4MAPK1ALDH1A1 | |
| SCHEMBL29140980 | 0.80 | TSHR (0.49) | TSHRTP53CYP3A4MAPK1ALDH1A1 | |
| SCHEMBL14361092 | 0.80 | TSHR (0.50) | TSHRTP53CYP3A4MAPK1ALDH1A1 | |
| SCHEMBL2291006 | 0.80 | NPC1 (0.57) | TSHRTP53CYP3A4MAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1556733-A4 | ELECTROCHROMIC DEVICES HAVING AN ELECTRON SHUTTLE | GENTEX CORP (US) | 2006-02-08 | — | — | EP | disclosed |
| EP-1556733-A1 | ELECTROCHROMIC DEVICES HAVING AN ELECTRON SHUTTLE | Gentex Corporation (US) | 2005-07-27 | — | — | EP | disclosed |
| WO-2004042463-A1 | ELECTROCHROMIC DEVICES HAVING AN ELECTRON SHUTTLE | GENTEX CORPORATION (US) | 2004-05-21 | — | — | WO | disclosed |