Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.41 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.41 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | CDK9 | P50750 | 1/20 | 0.41 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.41 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.41 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11511523 | 0.83 | FYN (0.47) | FYNKDM4EALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL11509322 | 0.80 | KDM4E (0.65) | FYNLMNAMAPTDYRK3CCNT1 | |
| SCHEMBL11623112 | 0.77 | KDM4E (0.65) | FYNSMN1; SMN2LMNAKDM4EALDH1A1 | |
| SCHEMBL11624931 | 0.76 | BRD4 (0.44) | FYNSMN1; SMN2RAB9ANPC1LMNA | |
| SCHEMBL11511075 | 0.74 | MET (0.62) | FYNRAB9ANPC1MET | |
| SCHEMBL11476225 | 0.73 | SMN1; SMN2 (0.52) | SMN1; SMN2RAB9ANPC1LMNAMAPT | |
| SCHEMBL11143235 | 0.70 | SMN1; SMN2 (0.46) | FYNSMN1; SMN2RAB9ANPC1LMNA | |
| SCHEMBL2614946 | 0.69 | KDM1A (0.50) | SMN1; SMN2RAB9ANPC1LMNAMAPT | |
| SCHEMBL10536971 | 0.69 | LMNA (0.55) | SMN1; SMN2RAB9ANPC1LMNAMAPT | |
| SCHEMBL10835032 | 0.68 | IDO1 (0.47) | SMN1; SMN2RAB9ANPC1MAPTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4159375-A | 6- AND 7-Aryl-1,2,4-triazolo[4,3-b]-1,2,4-triazines | AMERICAN CYANAMID COMPANY (US) | 1979-06-26 | — | — | US | claimed |