Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 5/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | TTR | P02766 | 2/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.44 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.44 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.44 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11513048 | 0.88 | MRGPRX4 (0.48) | MRGPRX4TDP1TTRCHRM1TSHR | |
| SCHEMBL9852618 | 0.81 | MRGPRX4 (0.49) | MRGPRX4TDP1TTRCHRM1TSHR | |
| SCHEMBL11512979 | 0.80 | PPARA (0.57) | TDP1TSHRPPARAMAPTSMN1; SMN2 | |
| SCHEMBL581884 | 0.78 | PPARA (0.59) | MRGPRX4TDP1TTRTSHRPPARA | |
| SCHEMBL11513032 | 0.76 | KMT2A (0.42) | TDP1TSHRMAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL10344600 | 0.75 | TDP1 (0.49) | MRGPRX4TDP1TTRCHRM1TSHR | |
| SCHEMBL8207859 | 0.74 | MRGPRX4 (0.55) | MRGPRX4TDP1TTRCHRM1PPARA | |
| SCHEMBL13876906 | 0.74 | SLC6A2 (0.48) | TDP1TTRTSHRMAPTL3MBTL1 | |
| SCHEMBL11512906 | 0.73 | CES1 (0.47) | TDP1TSHRMAPTL3MBTL1ALDH1A1 | |
| SCHEMBL29254277 | 0.73 | TDP1 (0.46) | TDP1TTRTSHRPPARAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4147791-A | 1-Substituted-1,2,4-triazole fungicidal compositions and methods for combatting fungi that infect or attack plants | BAYER AKTIENGESELLSCHAFT (DE) | 1979-04-03 | — | — | US | disclosed |
| US-4048318-A | 1-Substituted-1,2,4-triazole fungicides | BAYER AKTIENGESELLSCHAFT (DT) | 1977-09-13 | — | — | US | disclosed |