SCHEMBL581884

SCHEMBL581884

CC(C)(Oc1ccc(Cl)cc1Cl)C(=O)O

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 6/20 0.59
MAPT P10636 2/20 0.59
KMT2A Q03164 2/20 0.59
MEN1 O00255 1/20 0.59
CYP1A2 P05177 1/20 0.59
CYP3A4 P08684 1/20 0.59
CYP2D6 P10635 1/20 0.59
CYP2C19 P33261 1/20 0.59
TDP1 Q9NUW8 2/20 0.51
PPARG P37231 3/20 0.51
FABP2 P12104 1/20 0.51
SLC22A12 Q96S37 1/20 0.51
TSHR P16473 2/20 0.50
PPARD Q03181 3/20 0.47
TTR P02766 2/20 0.47
ACLY P53396 1/20 0.46
PTGDR2 Q9Y5Y4 1/20 0.46
KDM4E B2RXH2 1/20 0.45
ALDH1A1 P00352 1/20 0.45
HSD17B10 Q99714 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7978183 0.85 PPARA (0.57) PPARAMAPTKMT2AMEN1CYP1A2
SCHEMBL1331593 0.85 PPARA (0.57) PPARAMAPTKMT2AMEN1CYP1A2
SCHEMBL987343 0.85 PPARA (0.67) PPARAMAPTKMT2AMEN1CYP1A2
SCHEMBL6293391 0.84 TTR (0.49) PPARAMAPTKMT2AMEN1CYP1A2
SCHEMBL10344600 0.83 TDP1 (0.49) PPARAMAPTKMT2AMEN1CYP1A2
SCHEMBL1417566 0.83 PPARA (0.56) PPARAMAPTKMT2AMEN1CYP1A2
SCHEMBL233843 0.83 PPARA (0.47) PPARAMAPTKMT2AMEN1CYP1A2
SCHEMBL1369354 0.83 PPARA (0.56) PPARAMAPTKMT2AMEN1CYP1A2
SCHEMBL1045484 0.83 PPARA (0.55) PPARAMAPTKMT2AMEN1CYP1A2
SCHEMBL9416365 0.82 ESRRA (0.51) PPARAMAPTKMT2AMEN1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1217884-B1 METHOD FOR MATURATION OF CONIFER SOMATIC EMBRYOS WOODY PLANT BIOTECH APS (DK) 2007-02-21 EP claimed
US-6897065-B1 Method for maturation of conifer somatic embryos WOODY PLANT BIOTECH APS (DK) 2005-05-24 US claimed
EP-1217884-A1 METHOD FOR MATURATION OF CONIFER SOMATIC EMBRYOS Woody Plant Biotech APS (DK) 2002-07-03 EP claimed
WO-2001020972-A1 METHOD FOR MATURATION OF CONIFER SOMATIC EMBRYOS WOODY PLANT BIOTECH APS (DK) 2001-03-29 WO claimed
CN-118516415-B Method for preparing refined 2, 4-propionic acid by immobilized enzyme catalysis 南京科力硕生物科技有限公司 2024-10-29 CN disclosed
CN-118516415-A Method for preparing refined 2, 4-propionic acid by immobilized enzyme catalysis 南京科力硕生物科技有限公司 2024-08-20 CN disclosed
CN-116621697-A Preparation method of dextrorotation 2- (2, 4-dichlorophenoxy) propionic acid 南京工业大学 2023-08-22 CN disclosed
US-9718817-B2 Aryl and heteroaryl ether compounds as ROR gamma modulators GLENMARK PHARMACEUTICALS S.A. (CH) 2017-08-01 US disclosed
EP-3131880-A1 ARYL AND HETEROARYL ETHER COMPOUNDS AS ROR GAMMA MODULATORS Glenmark Pharmaceuticals S.A. (CH) 2017-02-22 EP disclosed
US-20170022195-A1 ARYL AND HETEROARYL ETHER COMPOUNDS AS ROR GAMMA MODULATORS GLENMARK PHARMACEUTICALS S.A. (CH) 2017-01-26 US disclosed
US-9487517-B2 Spiroimidazolone derivative CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2016-11-08 US disclosed
US-9487517-B2 Spiroimidazolone derivative CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2016-11-08 US disclosed
US-6897065-B1 Method for maturation of conifer somatic embryos WOODY PLANT BIOTECH APS (DK) 2005-05-24 US disclosed
EP-1217884-A1 METHOD FOR MATURATION OF CONIFER SOMATIC EMBRYOS Woody Plant Biotech APS (DK) 2002-07-03 EP disclosed
WO-2001020972-A1 METHOD FOR MATURATION OF CONIFER SOMATIC EMBRYOS WOODY PLANT BIOTECH APS (DK) 2001-03-29 WO disclosed
EP-0257378-B1 PYRIMIDINE DERIVATIVES, THEIR PREPARATION AND MEDICAMENTS CONTAINING THESE DERIVATIVES F. HOFFMANN-LA ROCHE AG (CH) 1991-07-03 EP disclosed
US-5010060-A Method of treating herpes simplex viral infection employing pyrimidine derivatives HOFFMANN-LA ROCHE INC. (US) 1991-04-23 US disclosed
EP-0387068-A1 Improving the enantioselectivity of biocatalytic resolution of racemic compounds WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 1990-09-12 EP disclosed
US-4851519-A AMIDO NUCLEOSIDES, VIRICIDES HOFFMANN-LA ROCHE INC. (US) 1989-07-25 US disclosed
EP-0257378-A1 Pyrimidine derivatives, their preparation and medicaments containing these derivatives F. HOFFMANN-LA ROCHE AG (CH) 1988-03-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170022195-A1 ARYL AND HETEROARYL ETHER COMPOUNDS AS ROR GAMMA MODULATORS RORB, RORA, RORC PPARA 63/4885MAPT 842/4885KMT2A 1211/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.