SCHEMBL11512437

SCHEMBL11512437

CCCS(=O)(=O)N(c1ccccc1)S(=O)(=O)C(F)(F)F

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.36
TSHR P16473 1/20 0.36
MAPK1 P28482 1/20 0.36
HSD17B10 Q99714 1/20 0.36
HDAC6 Q9UBN7 3/20 0.35
ESR1 P03372 3/20 0.34
MEN1 O00255 2/20 0.34
RORC P51449 2/20 0.34
ALDH1A1 P00352 1/20 0.34
HIF1A Q16665 1/20 0.34
EPAS1 Q99814 1/20 0.34
NR1H3 Q13133 2/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
CA12 O43570 1/20 0.33
CA2 P00918 1/20 0.33
CA9 Q16790 1/20 0.33
HSP90AA1 P07900 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10059165 0.81 HSP90AA1 (0.36) KMT2ATSHRMAPK1HSD17B10MEN1
SCHEMBL64494 0.80 CA2 (0.43) KMT2AESR1MEN1ALDH1A1NR1H3
SCHEMBL6191256 0.80 GRM2 (0.39) KMT2AMEN1RORCALDH1A1HSP90AA1
SCHEMBL624941 0.78 KMT2A (0.38) KMT2ATSHRMAPK1HSD17B10MEN1
SCHEMBL15082546 0.77 ALDH1A1 (0.37) KMT2AESR1MEN1ALDH1A1NR1H3
SCHEMBL2998813 0.74 TSHR (0.36) KMT2ATSHRMAPK1HSD17B10ESR1
SCHEMBL28384073 0.73 CA2 (0.35) KMT2ATSHRMAPK1HSD17B10MEN1
SCHEMBL5345859 0.72 CA12 (0.46) KMT2ATSHRMAPK1ESR1MEN1
SCHEMBL7920273 0.71 TSHR (0.41) KMT2ATSHRMAPK1HSD17B10ESR1
SCHEMBL16300054 0.71 MEN1 (0.33) KMT2AMEN1ALDH1A1NR1H3CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4163659-A HERBICIDES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1979-08-07 US disclosed
US-4076519-A N-substituted perfluoroalkanesulfonamides as herbicides MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1978-02-28 US disclosed