Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 2/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | AGER | Q15109 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | PLAU | P00749 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11513215 | 0.89 | CA12 (0.42) | PTGESMAPTF2PRSS1PRSS2 | |
| SCHEMBL11514188 | 0.87 | PTGES (0.46) | PTGESMAPTPOLBALDH1A1AGER | |
| SCHEMBL11511788 | 0.82 | F2 (0.46) | PTGESMAPTPOLBF2PRSS1 | |
| SCHEMBL11512631 | 0.80 | PTGES (0.57) | PTGESMAPTALDH1A1CA12CA9 | |
| SCHEMBL11512225 | 0.76 | PTGES (0.62) | PTGESMAPTALDH1A1CA12CA9 | |
| SCHEMBL11852635 | 0.76 | ALDH1A1 (0.49) | PTGESMAPTPOLBALDH1A1AGER | |
| SCHEMBL11512933 | 0.76 | PTGES (0.43) | PTGESALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL11513464 | 0.76 | TSHR (0.31) | — | |
| SCHEMBL11511705 | 0.75 | POLB (0.41) | PTGESMAPTPOLBALDH1A1AGER | |
| SCHEMBL11512557 | 0.74 | F2 (0.47) | MAPTPOLBF2PRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4175200-A | N,N-Disubstituted sulfonyl hydrazines | UNIROYAL, INC. (US) | 1979-11-20 | — | — | US | disclosed |