Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | GBA1 | P04062 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11511178 | 0.77 | TSHR (0.42) | ALDH1A1TDP1KMT2AL3MBTL1RAB9A | |
| SCHEMBL27829640 | 0.77 | ALDH1A1 (0.59) | ALDH1A1HTTTDP1KMT2AL3MBTL1 | |
| SCHEMBL28008005 | 0.74 | ALDH1A1 (0.63) | ALDH1A1HTTTDP1KMT2AL3MBTL1 | |
| SCHEMBL11513529 | 0.74 | MAPT (0.50) | ALDH1A1HTTKMT2ARAB9ANPC1 | |
| SCHEMBL3043522 | 0.73 | ALDH1A1 (0.59) | ALDH1A1HTTTDP1KMT2AL3MBTL1 | |
| SCHEMBL27952716 | 0.73 | ALDH1A1 (0.63) | ALDH1A1HTTTDP1KMT2AL3MBTL1 | |
| SCHEMBL1342303 | 0.73 | ALDH1A1 (0.63) | ALDH1A1HTTTDP1KMT2AL3MBTL1 | |
| SCHEMBL7221265 | 0.73 | KMT2A (0.58) | ALDH1A1HTTTDP1KMT2AL3MBTL1 | |
| SCHEMBL6561226 | 0.72 | ALDH1A1 (0.53) | ALDH1A1HTTTDP1KMT2AL3MBTL1 | |
| SCHEMBL27964357 | 0.72 | ALDH1A1 (0.53) | ALDH1A1HTTTDP1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4147791-A | 1-Substituted-1,2,4-triazole fungicidal compositions and methods for combatting fungi that infect or attack plants | BAYER AKTIENGESELLSCHAFT (DE) | 1979-04-03 | — | — | US | disclosed |
| US-4048318-A | 1-Substituted-1,2,4-triazole fungicides | BAYER AKTIENGESELLSCHAFT (DT) | 1977-09-13 | — | — | US | disclosed |