Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | RXRB | P28702 | 1/20 | 0.36 |
| ▸ | RXRG | P48443 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11390990 | 0.83 | HPGD (0.36) | TSHRNOTUMHPGDMEN1KMT2A | |
| SCHEMBL11272166 | 0.81 | TDP1 (0.43) | TSHRNOTUMHPGDTDP1ALDH1A1 | |
| SCHEMBL28319255 | 0.81 | TSHR (0.44) | TSHRNOTUMHPGDKMT2ALMNA | |
| SCHEMBL11841962 | 0.80 | TSHR (0.42) | TSHRNOTUMHPGDMEN1KMT2A | |
| SCHEMBL11539972 | 0.80 | TDP1 (0.36) | TSHRNOTUMHPGDMEN1KMT2A | |
| SCHEMBL11513946 | 0.78 | TSHR (0.56) | TSHRHPGDMEN1KMT2ALMNA | |
| SCHEMBL11300616 | 0.77 | L3MBTL1 (0.41) | TSHRHPGDMEN1KMT2ALMNA | |
| SCHEMBL11512545 | 0.77 | ALDH1A1 (0.56) | HPGDMEN1KMT2ATDP1L3MBTL1 | |
| SCHEMBL11513308 | 0.77 | SMN1; SMN2 (0.48) | TSHRNOTUMHPGDKMT2ALMNA | |
| SCHEMBL11823419 | 0.76 | MEN1 (0.40) | TSHRNOTUMHPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4147791-A | 1-Substituted-1,2,4-triazole fungicidal compositions and methods for combatting fungi that infect or attack plants | BAYER AKTIENGESELLSCHAFT (DE) | 1979-04-03 | — | — | US | disclosed |
| US-4048318-A | 1-Substituted-1,2,4-triazole fungicides | BAYER AKTIENGESELLSCHAFT (DT) | 1977-09-13 | — | — | US | disclosed |