Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11004645 | 0.92 | CA1 (0.38) | ALDH1A1KDM4EMAPTHPGDNPSR1 | |
| SCHEMBL10998937 | 0.91 | GAA (0.41) | ALDH1A1KDM4EMAPTHPGDLMNA | |
| SCHEMBL574908 | 0.90 | KDM4E (0.39) | ALDH1A1KDM4EMAPTHPGDUSP2 | |
| SCHEMBL10224539 | 0.90 | KDM4E (0.39) | ALDH1A1KDM4EMAPTHPGDUSP2 | |
| SCHEMBL574909 | 0.90 | KDM4E (0.39) | ALDH1A1KDM4EMAPTHPGDUSP2 | |
| SCHEMBL574175 | 0.90 | HPGD (0.43) | ALDH1A1KDM4EMAPTHPGDLMNA | |
| SCHEMBL10222901 | 0.90 | HPGD (0.43) | ALDH1A1KDM4EMAPTHPGDLMNA | |
| SCHEMBL573731 | 0.90 | HPGD (0.43) | ALDH1A1KDM4EMAPTHPGDLMNA | |
| SCHEMBL11510955 | 0.85 | ALDH1A1 (0.36) | ALDH1A1KDM4EMAPTHPGDLMNA | |
| SCHEMBL11512629 | 0.85 | LNPEP (0.45) | ALDH1A1KDM4EHPGDLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4172142-A | DIURETICS FOR TREATMENT OF EDEMA | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-10-23 | — | — | US | disclosed |