SCHEMBL11512759

SCHEMBL11512759

Cc1cc2cc3ccccc3cc2c(SSc2c(C)c(C)cc3cc4ccccc4cc23)c1C

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 5/20 0.38
CYP1A2 P05177 4/20 0.38
TSHR P16473 1/20 0.38
NQO1 P15559 1/20 0.36
ALDH1A1 P00352 6/20 0.36
HPGD P15428 2/20 0.36
HSD17B10 Q99714 2/20 0.36
TDP1 Q9NUW8 2/20 0.35
USP2 O75604 2/20 0.34
PAK1 Q13153 1/20 0.34
MAPT P10636 3/20 0.34
KDM4E B2RXH2 3/20 0.33
GAA P10253 2/20 0.33
RAB9A P51151 2/20 0.33
ELANE P08246 1/20 0.33
NPC1 O15118 1/20 0.33
GLA P06280 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
BRD4 O60885 1/20 0.32
HIF1A Q16665 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11674691 0.88 CYP2A6 (0.38) CYP2A6CYP1A2TSHRNQO1ALDH1A1
SCHEMBL8371731 0.86 CYP1A2 (0.47) CYP2A6CYP1A2TSHRALDH1A1HPGD
SCHEMBL11512764 0.85 CYP2A6 (0.35) CYP2A6CYP1A2TSHRNQO1ALDH1A1
SCHEMBL29512148 0.81 CYP1A2 (0.41) CYP2A6CYP1A2TSHRNQO1ALDH1A1
SCHEMBL1538428 0.81 CYP1A2 (0.41) CYP2A6CYP1A2TSHRNQO1ALDH1A1
SCHEMBL11674694 0.76 CYP2A6 (0.38) CYP2A6CYP1A2TSHRNQO1ALDH1A1
SCHEMBL4928668 0.76 ALDH1A1 (0.39) CYP2A6CYP1A2TSHRNQO1ALDH1A1
SCHEMBL8376482 0.76 BRD4 (0.40) CYP2A6CYP1A2TSHRNQO1ALDH1A1
SCHEMBL797237 0.75 NQO1 (0.46) CYP2A6CYP1A2TSHRNQO1ALDH1A1
SCHEMBL28217742 0.74 CYP1A2 (0.52) CYP2A6CYP1A2TSHRNQO1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4133830-A RECYCLING BY-PRODUCTS TO SUCCESSIVE RUNS TO IMPROVE YIELD STAUFFER CHEMICAL COMPANY (US) 1979-01-09 US disclosed
US-4000190-A FROM DIALKYL OR DIARYL DISULFIDES, PHOSPHORUS, AND PHOSPHORUS TRIHALIDE STAUFFER CHEMICAL COMPANY (US) 1976-12-28 US disclosed