Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 10/20 | 0.69 |
| ▸ | STAT3 | P40763 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | TTR | P02766 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13321693 | 0.91 | MRGPRX4 (0.71) | MRGPRX4STAT3NPC1RAB9APOLB | |
| SCHEMBL13321688 | 0.84 | MRGPRX4 (0.63) | MRGPRX4STAT3NPC1RAB9APOLB | |
| SCHEMBL2558867 | 0.83 | MRGPRX4 (0.62) | MRGPRX4NPC1RAB9APOLBHPGD | |
| SCHEMBL22480880 | 0.82 | MRGPRX4 (1.00) | MRGPRX4NPC1RAB9APOLBHPGD | |
| SCHEMBL1532826 | 0.79 | NPC1 (0.61) | MRGPRX4NPC1RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL14854821 | 0.77 | MRGPRX4 (0.55) | MRGPRX4NPC1RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL31568468 | 0.77 | MRGPRX4 (1.00) | MRGPRX4NPC1RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL22480615 | 0.77 | MRGPRX4 (1.00) | MRGPRX4NPC1RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL14985920 | 0.77 | ENPP2 (0.55) | MRGPRX4NPC1RAB9APOLBHPGD | |
| SCHEMBL22480822 | 0.77 | MRGPRX4 (1.00) | MRGPRX4NPC1RAB9APOLBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4169720-A | 2-[4-(4-Chlorophenoxymethyl)-phenoxy]-propionic acid compounds as herbicides | CELAMERCK GMBH & CO. KG (DE) | 1979-10-02 | — | — | US | disclosed |