Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 13/20 | 0.62 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2556022 | 0.88 | MRGPRX4 (0.51) | MRGPRX4ENPP2NPC1RAB9AHPGD | |
| SCHEMBL2554884 | 0.85 | ENPP2 (0.59) | MRGPRX4ENPP2NPC1RAB9AHPGD | |
| SCHEMBL2560162 | 0.85 | ENPP2 (0.56) | MRGPRX4ENPP2NPC1RAB9AHPGD | |
| SCHEMBL2554749 | 0.85 | MRGPRX4 (0.53) | MRGPRX4ENPP2KMT2A | |
| SCHEMBL13321693 | 0.85 | MRGPRX4 (0.71) | MRGPRX4NPC1RAB9APOLBHPGD | |
| SCHEMBL2554070 | 0.84 | MRGPRX4 (0.68) | MRGPRX4ENPP2NPC1RAB9AHPGD | |
| SCHEMBL11512939 | 0.83 | MRGPRX4 (0.69) | MRGPRX4NPC1RAB9APOLBHPGD | |
| SCHEMBL12260343 | 0.82 | ENPP2 (0.63) | MRGPRX4ENPP2NPC1RAB9AHPGD | |
| SCHEMBL8453 | 0.81 | ENPP2 (0.66) | MRGPRX4ENPP2NPC1RAB9AHPGD | |
| SCHEMBL29952431 | 0.81 | ENPP2 (0.66) | MRGPRX4ENPP2NPC1RAB9AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| US-11225655-B2 | Bi-functional complexes and methods for making and using such complexes | NUEVOLUTION A/S (DK) | 2022-01-18 | — | — | US | disclosed |
| EP-3540059-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | Nuevolution A/S (DK) | 2019-09-18 | — | — | EP | disclosed |
| EP-2558577-B1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION AS (DK) | 2018-12-12 | — | — | EP | disclosed |
| US-20130281324-A1 | BI-FUNCTINAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2013-10-24 | — | — | US | disclosed |
| EP-2558577-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | Nuevolution A/S (DK) | 2013-02-20 | — | — | EP | disclosed |
| WO-2011127933-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2011-10-20 | — | — | WO | disclosed |