Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.61 |
| ▸ | GPR35 | Q9HC97 | 4/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | TTR | P02766 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2659395 | 0.87 | ALDH1A1 (0.57) | ALDH1A1GPR35CYP3A4CYP1A2TDP1 | |
| SCHEMBL2085076 | 0.85 | ALDH1A1 (0.63) | ALDH1A1GPR35CYP3A4CYP1A2TDP1 | |
| SCHEMBL15285954 | 0.82 | GPR35 (0.55) | ALDH1A1GPR35CYP3A4CYP1A2TDP1 | |
| SCHEMBL6672266 | 0.80 | ALDH1A1 (0.63) | ALDH1A1GPR35CYP3A4CYP1A2TDP1 | |
| SCHEMBL5200622 | 0.79 | ALDH1A1 (0.66) | ALDH1A1GPR35CYP3A4CYP1A2TDP1 | |
| SCHEMBL1282898 | 0.79 | ALDH1A1 (0.68) | ALDH1A1GPR35CYP3A4CYP1A2TDP1 | |
| SCHEMBL20942948 | 0.79 | CYP1A2 (0.62) | ALDH1A1GPR35CYP3A4CYP1A2TDP1 | |
| SCHEMBL29720617 | 0.79 | ALDH1A1 (0.66) | ALDH1A1GPR35CYP3A4CYP1A2TDP1 | |
| SCHEMBL850072 | 0.78 | ALDH1A1 (0.55) | ALDH1A1GPR35CYP3A4CYP1A2TDP1 | |
| SCHEMBL2144780 | 0.78 | ALDH1A1 (0.63) | ALDH1A1GPR35CYP3A4CYP1A2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4171203-A | IN COMBINATION WITH A TETRAAMINOPYRIMIDING COUPLER SURFACTANTS AND THICKENERS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1979-10-16 | — | — | US | disclosed |