Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.66 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 4/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13532860 | 0.87 | SMN1; SMN2 (0.67) | LMNATP53SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL3155108 | 0.87 | SMN1; SMN2 (0.67) | LMNATP53SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL3155105 | 0.87 | SMN1; SMN2 (0.67) | LMNATP53SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL9821196 | 0.83 | SMN1; SMN2 (0.62) | LMNATP53SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL9821188 | 0.82 | TP53 (0.67) | LMNATP53SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL11553488 | 0.80 | LMNA (0.71) | LMNATP53SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL11559142 | 0.78 | LMNA (0.66) | LMNATP53SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL32688308 | 0.77 | TP53 (0.74) | LMNATP53SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL20573309 | 0.77 | TP53 (0.74) | LMNATP53SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL17445816 | 0.76 | TP53 (0.65) | LMNATP53SMN1; SMN2ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4162325-A | PHARMACEUTICAL ACTIVITY ON THE MNEMIC PROCESSES | UCB, SOCIETE ANONYME (BE) | 1979-07-24 | — | — | US | disclosed |