Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.67 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.45 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL563022 | 0.85 | TP53 (0.67) | TP53LMNASMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL1906215 | 0.85 | TP53 (0.67) | TP53LMNASMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL3155232 | 0.85 | TP53 (0.67) | TP53LMNASMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL32688308 | 0.84 | TP53 (0.74) | TP53LMNASMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL20573309 | 0.84 | TP53 (0.74) | TP53LMNASMN1; SMN2TSHRALDH1A1 | |
| Hydrochloric Acid SCHEMBL32688148 | 0.84 | TP53 (0.65) | TP53LMNASMN1; SMN2TSHRALDH1A1 | |
| Hydrochloric Acid SCHEMBL32688158 | 0.84 | TP53 (0.65) | TP53LMNASMN1; SMN2TSHRALDH1A1 | |
| Hydrochloric Acid SCHEMBL32688612 | 0.83 | TP53 (0.72) | TP53LMNASMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL11513286 | 0.82 | LMNA (0.66) | TP53LMNASMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL11115844 | 0.80 | TP53 (0.44) | TP53LMNASMN1; SMN2TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5021568-A | Lactam-1-acetic acid carbalkoxymethyl esters and method for preparing same | SHIPOV ALEXANDR G (SU) | 1991-06-04 | — | — | US | disclosed |
| US-4162325-A | PHARMACEUTICAL ACTIVITY ON THE MNEMIC PROCESSES | UCB, SOCIETE ANONYME (BE) | 1979-07-24 | — | — | US | disclosed |