Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | PLG | P00747 | 1/20 | 0.50 |
| ▸ | PLAT | P00750 | 1/20 | 0.50 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | GABRP | O00591 | 2/20 | 0.39 |
| ▸ | GABRD | O14764 | 2/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.39 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.39 |
| ▸ | GABRE | P78334 | 2/20 | 0.39 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28072511 | 0.93 | LMNA (0.48) | LMNAPLGPLATCES2CES1 | |
| SCHEMBL23751424 | 0.88 | LMNA (0.56) | LMNAPLGPLATCES2CES1 | |
| Monoethanolamine SCHEMBL1836886 | 0.86 | LMNA (0.50) | LMNAPLGPLATCES2CES1 | |
| Propylamine SCHEMBL7719000 | 0.84 | LMNA (0.48) | LMNAPLGPLATCES2CES1 | |
| SCHEMBL12492077 | 0.83 | CES2 (0.61) | LMNAPLGPLATCES2CES1 | |
| SCHEMBL12491655 | 0.83 | CES2 (0.61) | LMNAPLGPLATCES2CES1 | |
| SCHEMBL5493736 | 0.83 | CES2 (0.61) | LMNAPLGPLATCES2CES1 | |
| SCHEMBL8365391 | 0.83 | CES2 (0.61) | LMNAPLGPLATCES2CES1 | |
| SCHEMBL242069 | 0.83 | CES2 (0.61) | LMNAPLGPLATCES2CES1 | |
| SCHEMBL25212375 | 0.83 | CES2 (0.61) | LMNAPLGPLATCES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4171424-A | Polyesters containing units derived from metal salts of N-hydroxyalkylated branched α-aminoacids | CIBA-GEIGY CORPORATION (US) | 1979-10-16 | — | — | US | disclosed |
| US-4093639-A | HEAT RESISTANCE | CIBA-GEIGY CORPORATION (US) | 1978-06-06 | — | — | US | disclosed |