SCHEMBL11513312

SCHEMBL11513312

O=[C]COc1c(Cl)cc(Cl)cc1S(=O)(=O)O

nearest known ligand 0.39

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.39
CA2 P00918 2/20 0.39
CA9 Q16790 1/20 0.39
CXCR5 P32302 2/20 0.37
ACLY P53396 9/20 0.35
F2 P00734 2/20 0.33
PRSS1 P07477 2/20 0.33
PRSS2 P07478 2/20 0.33
PRSS3 P35030 2/20 0.33
TSHR P16473 1/20 0.32
NSD2 O96028 1/20 0.31
MMP14 P50281 1/20 0.31
CASP6 P55212 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL97291 0.81 CA1 (0.41) CA1CA2CA9TSHRTDP1
SCHEMBL11323103 0.78 ACLY (0.42) CA1CA2CA9CXCR5ACLY
Hydrochloric Acid SCHEMBL11323108 0.77 ACLY (0.52) ACLYTSHRTDP1
SCHEMBL21309558 0.75 ACLY (0.48) CA1CA2CA9ACLYF2
SCHEMBL6210588 0.71 HTT (0.45) TDP1
SCHEMBL21309559 0.71 CXCR5 (0.50) CA1CA2CA9CXCR5ACLY
SCHEMBL7766705 0.70 CA1 (0.43) CA1CA2CA9ACLYF2
SCHEMBL21294313 0.69 ACLY (0.41) CA1CA2CA9ACLYF2
SCHEMBL4258331 0.68 CA1 (0.48) CA1CA2CA9ACLYF2
SCHEMBL1267459 0.67 MAPT (0.42) TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4178445-A 7-(α-Substituted glycinamido)-3-substituted methyl-3-cephem-4-carboxylic acids and their derivatives FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1979-12-11 US claimed