Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | INPPL1 | O15357 | 7/20 | 0.37 |
| ▸ | INPP5A | Q14642 | 5/20 | 0.36 |
| ▸ | AKT1 | P31749 | 1/20 | 0.35 |
| ▸ | INPP5B | P32019 | 2/20 | 0.34 |
| ▸ | F2 | P00734 | 3/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.33 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.33 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.33 |
| ▸ | ACLY | P53396 | 3/20 | 0.33 |
| ▸ | SRC | P12931 | 2/20 | 0.33 |
| ▸ | NSD2 | O96028 | 1/20 | 0.32 |
| ▸ | MMP14 | P50281 | 1/20 | 0.32 |
| ▸ | CASP6 | P55212 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25259132 | 0.80 | INPPL1 (0.48) | CA1CA2CA9INPPL1INPP5A | |
| SCHEMBL21309558 | 0.76 | ACLY (0.48) | CA1CA2CA9F2PRSS1 | |
| SCHEMBL21309559 | 0.72 | CXCR5 (0.50) | CA1CA2CA9F2PRSS1 | |
| SCHEMBL10674455 | 0.71 | CA1 (0.47) | CA1CA2CA9F2PRSS1 | |
| SCHEMBL9951728 | 0.70 | CA1 (0.43) | CA1CA2CA9F2PRSS1 | |
| SCHEMBL11513312 | 0.70 | CA1 (0.39) | CA1CA2CA9F2PRSS1 | |
| SCHEMBL11323103 | 0.70 | ACLY (0.42) | CA1CA2CA9ACLY | |
| SCHEMBL1648602 | 0.70 | CA1 (0.66) | CA1CA2F2PRSS1PRSS2 | |
| SCHEMBL9589745 | 0.70 | CA1 (0.66) | CA1CA2F2PRSS1PRSS2 | |
| SCHEMBL4258331 | 0.69 | CA1 (0.48) | CA1CA2CA9F2PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1102991-A2 | DIAGNOSTIC ASSAY REQUIRING A SMALL SAMPLE OF BIOLOGICAL FLUID | ABBOTT LABORATORIES (US) | 2001-05-30 | — | — | EP | disclosed |
| WO-1999064620-A2 | DIAGNOSTIC ASSAY REQUIRING A SMALL SAMPLE OF BIOLOGICAL FLUID | ABBOTT LABORATORIES (US) | 1999-12-16 | — | — | WO | disclosed |