Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | LIPE | Q05469 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | ALPG | P10696 | 1/20 | 0.39 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.38 |
| ▸ | CDK1 | P06493 | 1/20 | 0.38 |
| ▸ | CDK4 | P11802 | 1/20 | 0.38 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.38 |
| ▸ | CCND1 | P24385 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9232295 | 0.86 | TDP1 (0.44) | RAB9ASMN1; SMN2TDP1L3MBTL1MAPT | |
| SCHEMBL183414 | 0.84 | MAPT (0.48) | RAB9ASMN1; SMN2TDP1L3MBTL1MAPT | |
| SCHEMBL4833255 | 0.83 | ABCB1 (0.45) | RAB9ASMN1; SMN2HTR1ADRD2 | |
| SCHEMBL5475735 | 0.82 | MAOB (0.51) | L3MBTL1MAPTMAOBMAPK14 | |
| SCHEMBL1616224 | 0.81 | MAPT (0.55) | SMN1; SMN2TDP1L3MBTL1MAPTMAPK1 | |
| SCHEMBL6996715 | 0.79 | APP (0.47) | SMN1; SMN2TDP1L3MBTL1MAPTMAPK1 | |
| SCHEMBL1099955 | 0.79 | MAPT (0.44) | TDP1L3MBTL1MAPTMAPK1HTR1A | |
| SCHEMBL5315646 | 0.79 | APP (0.47) | RAB9ASMN1; SMN2TDP1L3MBTL1MAPT | |
| SCHEMBL1446254 | 0.79 | HPGD (0.46) | RAB9ASMN1; SMN2TDP1L3MBTL1MAPT | |
| SCHEMBL339374 | 0.78 | HTR1A (0.53) | RAB9ASMN1; SMN2TDP1L3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102869256-A | Catechol O-methyltransferase inhibitors and their use in the treatment of psychotic disorders | MERCK SHARP & DOHME | 2013-01-09 | — | — | CN | disclosed |
| CN-101103013-B | 1-thio-D-glucitol derivatives | TAISHO PHARMACEUTICAL CO LTD | 2012-05-23 | — | — | CN | disclosed |
| CN-101309893-B | Process for producing biphenyl | SYNGENTA PARTICIPATIONS AG | 2012-03-28 | — | — | CN | disclosed |
| CN-101309893-A | Process for producing biphenyl | SYNGENTA PARTICIPATIONS AG (CH) | 2008-11-19 | — | — | CN | disclosed |
| CN-101103013-A | 1-thio-D-glucitol derivatives | TAISHO PHARMACEUTICAL CO LTD (JP) | 2008-01-09 | — | — | CN | disclosed |
| CN-1984898-A | Process for production of azulene derivatives and intermediates for the synthesis of the same | ASTELLAS PHARMA INC (JP) | 2007-06-20 | — | — | CN | disclosed |
| CN-1288143-C | Azulene derivatives and salts thereof | YAMANOUCHI PHARMA CO LTD (JP) | 2006-12-06 | — | — | CN | disclosed |
| CN-1671682-A | Azulene derivatives and salts thereof | YAMANOUCHI PHARMA CO LTD (JP) | 2005-09-21 | — | — | CN | disclosed |
| US-4147554-A | 5,6-DIHYDRO-PYRROLO(2,1-A)ISOQUINOLINES | MITSUBISHI PAPER MILLS, LTD. (JP) | 1979-04-03 | — | — | US | disclosed |