Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A2 | P19784 | 4/20 | 0.54 |
| ▸ | CSNK2A1 | P68400 | 4/20 | 0.54 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | FABP4 | P15090 | 2/20 | 0.42 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11807352 | 0.89 | APEX1 (0.55) | CSNK2A2CSNK2A1APEX1FABP4FABP5 | |
| SCHEMBL411981 | 0.82 | APEX1 (0.54) | APEX1FABP4FABP5MAPK1KDM4E | |
| SCHEMBL11514305 | 0.80 | TSHR (0.44) | CSNK2A2CSNK2A1SMN1; SMN2LMNA | |
| SCHEMBL11514212 | 0.77 | TNF (0.60) | KDM4ECYP1A2 | |
| SCHEMBL25465028 | 0.76 | PTGS1 (0.53) | APEX1FABP4FABP5MEN1KMT2A | |
| SCHEMBL30976974 | 0.75 | APEX1 (0.47) | CSNK2A2CSNK2A1APEX1FABP4FABP5 | |
| SCHEMBL11817897 | 0.75 | CSNK2A2 (0.50) | CSNK2A2CSNK2A1APEX1 | |
| SCHEMBL25465029 | 0.74 | PTGS1 (0.57) | APEX1FABP4FABP5MEN1KMT2A | |
| SCHEMBL6520401 | 0.73 | APEX1 (0.78) | APEX1FABP4FABP5MAPK1KDM4E | |
| SCHEMBL3771053 | 0.71 | FABP4 (0.46) | CSNK2A2CSNK2A1APEX1FABP4FABP5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4161603-A | HEAT RESISTANT POLYESTERS | CIBA-GEIGY CORPORATION (US) | 1979-07-17 | — | — | US | disclosed |