Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.69 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.68 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.64 |
| ▸ | IDE | P14735 | 2/20 | 0.63 |
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | ATM | Q13315 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11699162 | 0.85 | L3MBTL1 (0.67) | POLBL3MBTL1RXFP1ALDH1A1IDE | |
| SCHEMBL10919867 | 0.85 | CYP1A2 (0.69) | POLBL3MBTL1RXFP1ALDH1A1IDE | |
| SCHEMBL11694093 | 0.83 | POLB (0.64) | POLBL3MBTL1RXFP1ALDH1A1IDE | |
| SCHEMBL11517061 | 0.81 | POLB (0.63) | POLBL3MBTL1RXFP1ALDH1A1IDE | |
| SCHEMBL11513877 | 0.81 | POLB (0.62) | POLBL3MBTL1RXFP1ALDH1A1IDE | |
| SCHEMBL11697210 | 0.80 | POLB (0.61) | POLBL3MBTL1RXFP1ALDH1A1IDE | |
| SCHEMBL11695830 | 0.79 | ATM (0.63) | POLBL3MBTL1RXFP1ALDH1A1IDE | |
| SCHEMBL11696189 | 0.79 | POLB (0.60) | POLBL3MBTL1RXFP1ALDH1A1IDE | |
| SCHEMBL11697035 | 0.78 | POLB (0.59) | POLBL3MBTL1RXFP1ALDH1A1IDE | |
| SCHEMBL11696518 | 0.78 | L3MBTL1 (0.69) | POLBL3MBTL1RXFP1ALDH1A1IDE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE30024-E | ANTIALLERGENS | STERLING DRUG INC. (US) | 1979-06-05 | — | — | US | disclosed |
| US-4118571-A | ANTIALLERGENS | STERLING DRUG INC. (US) | 1978-10-03 | — | — | US | disclosed |
| US-4086233-A | ANTIALLERGENS | STERLING DRUG INC. (US) | 1978-04-25 | — | — | US | disclosed |
| US-4053475-A | ANTI-ALLERGIC AGENTS | STERLING DRUG INC. (US) | 1977-10-11 | — | — | US | disclosed |
| US-4032523-A | ANTIALLERGENS | STERLING DRUG INC. (US) | 1977-06-28 | — | — | US | disclosed |
| US-4008235-A | ANTIALLERGIC | STERLING DRUG INC. (US) | 1977-02-15 | — | — | US | disclosed |