Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.37 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.37 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11513361 | 0.79 | MAPK1 (0.53) | MAPK1ALDH1A1MAPTL3MBTL1CYP3A4 | |
| SCHEMBL11512954 | 0.75 | ALDH1A1 (0.55) | MAPK1ALDH1A1MAPTL3MBTL1CYP3A4 | |
| SCHEMBL27319132 | 0.74 | GPR35 (0.55) | MAPK1ALDH1A1MAPTL3MBTL1CYP3A4 | |
| SCHEMBL12863895 | 0.72 | GPR35 (0.57) | MAPK1ALDH1A1MAPTL3MBTL1CYP3A4 | |
| SCHEMBL9501864 | 0.72 | GPR35 (0.57) | MAPK1ALDH1A1MAPTL3MBTL1CYP3A4 | |
| SCHEMBL11514412 | 0.70 | ALDH1A1 (0.54) | MAPK1ALDH1A1MAPTL3MBTL1CYP3A4 | |
| SCHEMBL19737473 | 0.69 | ALDH1A1 (0.49) | MAPK1ALDH1A1MAPTL3MBTL1CYP3A4 | |
| SCHEMBL19737438 | 0.68 | ALDH1A1 (0.55) | MAPK1ALDH1A1MAPTL3MBTL1CYP3A4 | |
| SCHEMBL7082752 | 0.68 | MAPK1 (0.50) | MAPK1ALDH1A1MAPTL3MBTL1TDP1 | |
| SCHEMBL19420578 | 0.68 | GPR35 (0.61) | MAPK1ALDH1A1MAPTL3MBTL1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4087460-A | HERBICIDES, PLANT GROWTH REGULATORS, CHEMICAL INTERMEDIATES | ELI LILLY AND COMPANY (US) | 1978-05-02 | — | — | US | claimed |
| US-4143073-A | REACTION OF SUBSTITUTED N-ALKOXY-2,6-DINITROANILINES WITH ALKYL OR ALKENYL HALIDE IN PRESENCE OF SODIUM HYDRIDE | ELI LILLY AND COMPANY (US) | 1979-03-06 | — | — | US | disclosed |
| US-4087460-A | HERBICIDES, PLANT GROWTH REGULATORS, CHEMICAL INTERMEDIATES | ELI LILLY AND COMPANY (US) | 1978-05-02 | — | — | US | disclosed |