Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KAT2B | Q92831 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28908599 | 0.81 | KMT2A (0.70) | TSHRKMT2AHSD17B10MEN1ALDH1A1 | |
| SCHEMBL11514458 | 0.80 | ELANE (0.47) | TSHRKMT2AHSD17B10MEN1KAT2B | |
| SCHEMBL2990451 | 0.80 | KMT2A (0.50) | TSHRKMT2AHSD17B10MEN1KAT2B | |
| SCHEMBL5161619 | 0.79 | MGLL (0.54) | TSHRKAT2BALDH1A1MAPTLMNA | |
| SCHEMBL15511371 | 0.79 | SMN1; SMN2 (0.54) | TSHRHSD17B10KAT2BALDH1A1MAPT | |
| SCHEMBL11513447 | 0.78 | MAPK1 (0.64) | KMT2AHSD17B10MEN1ALDH1A1TDP1 | |
| SCHEMBL7542052 | 0.75 | HDAC8 (0.67) | KMT2AHSD17B10MEN1ALDH1A1TDP1 | |
| SCHEMBL8779372 | 0.75 | HDAC8 (0.67) | KMT2AHSD17B10MEN1ALDH1A1TDP1 | |
| SCHEMBL7548208 | 0.75 | HDAC8 (0.67) | KMT2AHSD17B10MEN1ALDH1A1TDP1 | |
| SCHEMBL7542107 | 0.75 | HDAC8 (0.67) | KMT2AHSD17B10MEN1ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4161603-A | HEAT RESISTANT POLYESTERS | CIBA-GEIGY CORPORATION (US) | 1979-07-17 | — | — | US | disclosed |