Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.68 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.68 |
| ▸ | CASP7 | P55210 | 1/20 | 0.68 |
| ▸ | MAPT | P10636 | 8/20 | 0.56 |
| ▸ | MEN1 | O00255 | 5/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | GAA | P10253 | 3/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.52 |
| ▸ | GFER | P55789 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.48 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.46 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.46 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7167600 | 0.89 | TDP1 (0.79) | TDP1MAPK1ALDH1A1L3MBTL1CASP7 | |
| SCHEMBL26468007 | 0.87 | TDP1 (0.77) | TDP1MAPK1ALDH1A1L3MBTL1CASP7 | |
| SCHEMBL7168043 | 0.84 | TDP1 (0.72) | TDP1MAPK1ALDH1A1L3MBTL1CASP7 | |
| SCHEMBL11515701 | 0.84 | MAPT (0.72) | TDP1MAPK1ALDH1A1L3MBTL1CASP7 | |
| SCHEMBL16755402 | 0.82 | LMNA (0.52) | TDP1MAPK1ALDH1A1L3MBTL1MAPT | |
| SCHEMBL3323396 | 0.82 | MAPT (0.51) | TDP1MAPK1ALDH1A1L3MBTL1CASP7 | |
| SCHEMBL7171202 | 0.82 | MAPK1 (0.74) | TDP1MAPK1ALDH1A1L3MBTL1CASP7 | |
| SCHEMBL230292 | 0.81 | TDP1 (1.00) | TDP1MAPK1ALDH1A1L3MBTL1CASP7 | |
| SCHEMBL31333098 | 0.81 | TDP1 (1.00) | TDP1MAPK1ALDH1A1L3MBTL1CASP7 | |
| SCHEMBL7303310 | 0.81 | TDP1 (0.68) | TDP1MAPK1ALDH1A1L3MBTL1CASP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3950127-A | HAIR DYE COMPOSITIONS CONTAINING NITRODIPHENYLAMINE DYES AND METHOD FOR DYEING HAIR THEREWITH | CLAIROL INCORPORATED (US) | 1976-04-13 | — | — | US | claimed |
| US-4179436-A | DYEING POLYESTERS | BAYER AKTIENGESELLSCHAFT (DE) | 1979-12-18 | — | — | US | disclosed |
| US-4163013-A | Diphenylamine-azo-hydrocarbylsulfonylphenyl dyestuffs | BAYER AKTIENGESELLSCHAFT (DE) | 1979-07-31 | — | — | US | disclosed |
| US-4021486-A | Hydroxyalkyl-amino nitrodiphenylamine compounds useful as hair dyes | CLAIROL INCORPORATED (US) | 1977-05-03 | — | — | US | disclosed |
| US-3950127-A | HAIR DYE COMPOSITIONS CONTAINING NITRODIPHENYLAMINE DYES AND METHOD FOR DYEING HAIR THEREWITH | CLAIROL INCORPORATED (US) | 1976-04-13 | — | — | US | disclosed |