Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | HSD17B3 | P37058 | 8/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | EYA3 | Q99504 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | ESR1 | P03372 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11514944 | 0.85 | MEN1 (0.55) | TYRHTTTSHRMAPTMEN1 | |
| SCHEMBL28168334 | 0.84 | LIG1 (0.53) | TYRHTTTSHRMAPTMEN1 | |
| SCHEMBL18598996 | 0.82 | TYR (0.61) | TYRHTTTSHRMAPTMEN1 | |
| SCHEMBL17926251 | 0.82 | TYR (0.61) | TYRHTTTSHRMAPTMEN1 | |
| SCHEMBL4302296 | 0.79 | HSD17B3 (0.50) | TP53CYP3A4HSD17B3PTPN1EYA3 | |
| SCHEMBL28496814 | 0.78 | RXRA (0.48) | HTTTSHRMAPTMEN1TP53 | |
| SCHEMBL29089973 | 0.76 | CYP3A4 (0.63) | TYRHTTTSHRMAPTMEN1 | |
| SCHEMBL5710052 | 0.76 | MEN1 (0.56) | TYRHTTMAPTMEN1TP53 | |
| SCHEMBL30320281 | 0.76 | MEN1 (0.56) | TYRHTTMAPTMEN1TP53 | |
| Benzene SCHEMBL11504828 | 0.75 | MAPT (0.61) | TYRHTTTSHRMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999007694-A1 | COMPOUNDS AND USES THEREOF | ELI LILLY AND COMPANY (US) | 1999-02-18 | — | — | WO | disclosed |