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Styrene

Styrene

SCHEMBL11515324

C=CC(=O)NC(=O)C(C)=CC(CCCC)=C(C=CC#N)C(=O)O.C=Cc1ccccc1

nearest known ligand 0.32

Full drug profile on Sugi Atlas →

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ EGFR P00533 1/20 0.32
▸ HDAC3 O15379 1/20 0.32
▸ LMNA P02545 1/20 0.32
▸ TDP1 Q9NUW8 1/20 0.31
▸ ALDH1A1 P00352 1/20 0.30
▸ POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL16178706 0.80 LMNA (0.35) EGFRHDAC3LMNATDP1ALDH1A1
Styrene SCHEMBL10876445 0.78 KDM4E (0.41) EGFRLMNATDP1ALDH1A1POLB
SCHEMBL3430615 0.74 HDAC3 (0.44) EGFRHDAC3LMNATDP1ALDH1A1
SCHEMBL183140 0.73 HDAC3 (0.43) EGFRHDAC3LMNATDP1ALDH1A1
SCHEMBL9067799 0.72 HDAC3 (0.41) EGFRHDAC3LMNATDP1ALDH1A1
Styrene SCHEMBL7116740 0.71 KDM4E (0.44) EGFRHDAC3LMNATDP1ALDH1A1
SCHEMBL10705055 0.71 HDAC3 (0.45) EGFRHDAC3LMNATDP1ALDH1A1
Styrene SCHEMBL183141 0.68 LMNA (0.41) EGFRHDAC3LMNATDP1ALDH1A1
Styrene SCHEMBL3430856 0.68 LMNA (0.39) EGFRHDAC3LMNATDP1ALDH1A1
SCHEMBL7215358 0.67 CES1 (0.33) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4163034-A DECYCLIZATION, ESTERIFICATION; FIREPROOFING HOECHST AG. (DE) 1979-07-31 — — US disclosed
US-4096208-A FIREPROOFING AGENTS HOECHST AKTIENGESELLSCHAFT (DT) 1978-06-20 — — US disclosed