Styrene

Styrene

SCHEMBL16178706

C=Cc1ccccc1.CCCCC(C=CC(=O)O)=C(C=CC#N)C(=O)O

nearest known ligand 0.35

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.35
TDP1 Q9NUW8 2/20 0.34
TSHR P16473 2/20 0.33
HDAC3 O15379 2/20 0.33
EGFR P00533 1/20 0.33
CES2 O00748 1/20 0.33
CES1 P23141 1/20 0.33
ALDH1A1 P00352 1/20 0.32
ATG4B Q9Y4P1 8/20 0.32
PLA2G1B P04054 7/20 0.32
TNKS O95271 1/20 0.31
HDAC4 P56524 1/20 0.31
HDAC1 Q13547 1/20 0.31
HCAR2 Q8TDS4 1/20 0.31
HDAC7 Q8WUI4 1/20 0.31
HDAC2 Q92769 1/20 0.31
HDAC10 Q969S8 1/20 0.31
HDAC11 Q96DB2 1/20 0.31
HDAC8 Q9BY41 1/20 0.31
TNKS2 Q9H2K2 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3430615 0.84 HDAC3 (0.44) LMNATDP1HDAC3EGFRALDH1A1
SCHEMBL183140 0.83 HDAC3 (0.43) LMNATDP1HDAC3EGFRALDH1A1
SCHEMBL9067799 0.82 HDAC3 (0.41) LMNATDP1HDAC3EGFRALDH1A1
SCHEMBL16178704 0.81 HCAR2 (0.39) CES2CES1ATG4BPLA2G1BHCAR2
Styrene SCHEMBL11515324 0.80 EGFR (0.32) LMNATDP1HDAC3EGFRALDH1A1
SCHEMBL987787 0.78 HDAC3 (0.49) LMNATDP1HDAC3EGFRALDH1A1
SCHEMBL7948133 0.77 TDP1 (0.42) TDP1HDAC3EGFRALDH1A1TNKS
Styrene SCHEMBL183141 0.75 LMNA (0.41) LMNATDP1TSHRHDAC3EGFR
Styrene SCHEMBL3430856 0.75 LMNA (0.39) LMNATDP1TSHRHDAC3EGFR
Styrene SCHEMBL17644789 0.74 ALDH1A1 (0.40) LMNATDP1TSHRHDAC3ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3525043-B1 METHOD OF PRODUCING TONERS ESHIBITING REDUCED MACHINE ULTRAFINE PARTICLE (UFP) EMISSIONS XEROX CORP (US) 2023-10-25 EP disclosed
EP-3680719-A1 NON-BISPHENOL-A EMULSION AGGREGATION TONER AND PROCESS Xerox Corporation (US) 2020-07-15 EP disclosed
US-10409185-B2 Toners exhibiting reduced machine ultrafine particle (UFP) emissions and related methods XEROX CORPORATION (US) 2019-09-10 US disclosed
EP-3525043-A1 TONERS EXHIBITING REDUCED MACHINE ULTRAFINE PARTICLE (UFP) EMISSIONS AND RELATED METHODS Xerox Corporation (US) 2019-08-14 EP disclosed
US-20190243271-A1 TONERS EXHIBITING REDUCED MACHINE ULTRAFINE PARTICLE (UFP) EMISSIONS AND RELATED METHODS XEROX CORPORATION 2019-08-08 US disclosed
US-9639015-B2 Emulsion aggregation toners XEROX CORPORATION (US) 2017-05-02 US disclosed
US-20150160574-A1 EMULSION AGGREGATION TONERS XEROX CORPORATION (US) 2015-06-11 US disclosed
US-9029057-B2 Single component developer composition XEROX CORPORATION (US) 2015-05-12 US disclosed
US-20140315127-A1 Single Component Developer Composition XEROX CORPORATION (US) 2014-10-23 US disclosed