Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 6/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | AHR | P35869 | 1/20 | 0.45 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.44 |
| ▸ | BCL9 | O00512 | 1/20 | 0.43 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.43 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.42 |
| ▸ | CACNG8 | Q8WXS5 | 1/20 | 0.42 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.41 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11515388 | 0.90 | MAOB (0.50) | MAOBGAAKDM4EALDH1A1KMT2A | |
| SCHEMBL28346887 | 0.82 | GAA (0.52) | MAOBGAAALDH1A1KMT2AAHR | |
| SCHEMBL21604 | 0.82 | GAA (0.46) | MAOBGAAAHREIF2AK2EPHX2 | |
| SCHEMBL6981292 | 0.81 | AHR (0.51) | MAOBGAAAHREIF2AK2EPHX2 | |
| SCHEMBL6980695 | 0.80 | GAA (0.48) | MAOBGAAAHREIF2AK2GRIA1 | |
| SCHEMBL27691373 | 0.80 | MAOB (0.50) | MAOBGAAKMT2AAHREIF2AK2 | |
| SCHEMBL10375833 | 0.78 | MAOB (0.65) | MAOBAHREIF2AK2PDE3BPDE3A | |
| SCHEMBL10828352 | 0.78 | AHR (0.51) | MAOBGAAAHREIF2AK2EPHX2 | |
| SCHEMBL689457 | 0.78 | MAOB (0.62) | MAOBGAAKMT2AAHREIF2AK2 | |
| SCHEMBL14815914 | 0.77 | MAOB (0.52) | MAOBGAAKDM4EALDH1A1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101987848-B | New dihydroindolone derivatives, method of preparing same and pharmaceutical compositions containing the same | SERVIER LAB | 2014-06-18 | — | — | CN | disclosed |
| CN-101987848-A | New dihydroindolone derivatives, method of preparing same and pharmaceutical compositions containing them | SERVIER LAB | 2011-03-23 | — | — | CN | disclosed |