Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 1/20 | 0.53 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.48 |
| ▸ | LDLR | P01130 | 1/20 | 0.45 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 4/20 | 0.40 |
| ▸ | USP2 | O75604 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 8/20 | 0.38 |
| ▸ | MAPT | P10636 | 6/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL822807 | 0.80 | HPGDS (0.77) | HPGDSMAP4K4LDLRPCSK9CYP1A2 | |
| SCHEMBL11516035 | 0.73 | HSD11B1 (0.44) | CYP1A2MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL15244918 | 0.69 | FYN (0.51) | HPGDSMAP4K4GAAMAPTKDM4E | |
| SCHEMBL2365544 | 0.69 | HPGDS (1.00) | HPGDSMAP4K4LDLRPCSK9CYP1A2 | |
| SCHEMBL15244919 | 0.68 | MAP4K4 (0.47) | HPGDSMAP4K4LDLRPCSK9CYP1A2 | |
| SCHEMBL15244922 | 0.67 | PIM1 (0.52) | HPGDSMAP4K4 | |
| SCHEMBL2835874 | 0.67 | HPGDS (0.67) | HPGDSMAP4K4LDLRPCSK9CYP1A2 | |
| SCHEMBL208711 | 0.67 | HDAC4 (0.43) | KDM4EKMT2AHSD17B10L3MBTL1 | |
| SCHEMBL743962 | 0.67 | IDO1 (0.50) | HPGDSLDLRPCSK9 | |
| SCHEMBL19868973 | 0.66 | GAA (0.44) | HPGDSMAP4K4LDLRPCSK9CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4164480-A | POLYMER STABILIZERS | EASTMAN KODAK COMPANY (US) | 1979-08-14 | — | — | US | disclosed |
| US-4105631-A | MULTICHROMOPHORIC ULTRAVIOLET STABILIZERS AND THEIR USE IN ORGANIC COMPOSITIONS | EASTMAN KODAK COMPANY (US) | 1978-08-08 | — | — | US | disclosed |
| US-4043973-A | PIGMENTS, COLORANTS, FILLERS, REINFORCING AGENTS | EASTMAN KODAK COMPANY (US) | 1977-08-23 | — | — | US | disclosed |
| US-3939115-A | OXADIAZOLES | EASTMAN KODAK COMPANY (US) | 1976-02-17 | — | — | US | disclosed |
| US-3936419-A | Multichromophoric ultraviolet stabilizers and their use in organic compositions | EASTMAN KODAK COMPANY (US) | 1976-02-03 | — | — | US | disclosed |