SCHEMBL11515547

SCHEMBL11515547

Cc1nc(-c2c[c]ccc2)oc1-c1cc[c]cc1

nearest known ligand 0.33

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.33
MAPK13 O15264 1/20 0.32
MAPK12 P53778 1/20 0.32
MAPK11 Q15759 1/20 0.32
MAPK14 Q16539 1/20 0.32
KDM4E B2RXH2 1/20 0.31
ALDH1A1 P00352 1/20 0.31
CYP1A2 P05177 1/20 0.31
HPGD P15428 1/20 0.31
MAPK1 P28482 1/20 0.31
CYP2C19 P33261 1/20 0.31
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11514956 0.85 IKBKB (0.37) GAAMAPK13MAPK12MAPK11MAPK14
SCHEMBL1570167 0.81 GAA (0.39) GAAKDM4EALDH1A1CYP1A2HPGD
SCHEMBL869242 0.75 GAA (0.51) GAAMAPK13MAPK12MAPK11MAPK14
SCHEMBL272772 0.73 NPC1 (0.50) GAAMAPK13MAPK12MAPK11MAPK14
SCHEMBL225236 0.69 NPC1 (0.42) GAAKDM4EALDH1A1HPGDHSD17B10
SCHEMBL11372288 0.69 SMN1; SMN2 (0.47) GAAKDM4EALDH1A1CYP1A2HPGD
SCHEMBL482742 0.68 MAPK13 (0.45) GAAMAPK13MAPK12MAPK11MAPK14
SCHEMBL509984 0.68 ALDH1A1 (0.33) ALDH1A1
SCHEMBL62127 0.68 ACHE (0.50) ALDH1A1
SCHEMBL11377496 0.68 SMN1; SMN2 (0.68) KDM4EALDH1A1CYP1A2HPGDMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4164480-A POLYMER STABILIZERS EASTMAN KODAK COMPANY (US) 1979-08-14 US disclosed
US-4105631-A MULTICHROMOPHORIC ULTRAVIOLET STABILIZERS AND THEIR USE IN ORGANIC COMPOSITIONS EASTMAN KODAK COMPANY (US) 1978-08-08 US disclosed
US-4043973-A PIGMENTS, COLORANTS, FILLERS, REINFORCING AGENTS EASTMAN KODAK COMPANY (US) 1977-08-23 US disclosed
US-3939115-A OXADIAZOLES EASTMAN KODAK COMPANY (US) 1976-02-17 US disclosed
US-3936419-A Multichromophoric ultraviolet stabilizers and their use in organic compositions EASTMAN KODAK COMPANY (US) 1976-02-03 US disclosed