Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | APP | P05067 | 2/20 | 0.53 |
| ▸ | SNCA | P37840 | 2/20 | 0.53 |
| ▸ | TNF | P01375 | 1/20 | 0.53 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | BCHE | P06276 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | INSR | P06213 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL31063723 | 0.98 | MAPT (0.61) | MAPTKDM4ELMNAAPPSNCA | |
| SCHEMBL14434817 | 0.83 | MAPT (0.61) | MAPTKDM4ELMNAAPPSNCA | |
| Iodide SCHEMBL31063683 | 0.82 | MAPT (0.64) | MAPTKDM4ELMNAAPPSNCA | |
| SCHEMBL29685190 | 0.80 | APP (0.50) | MAPTKDM4ELMNAAPPSNCA | |
| SCHEMBL11516326 | 0.80 | MAPT (0.45) | MAPTKDM4ELMNAAPPSNCA | |
| SCHEMBL9031987 | 0.80 | APP (0.50) | MAPTKDM4ELMNAAPPSNCA | |
| Iodide SCHEMBL31063860 | 0.79 | MAPT (0.47) | MAPTKDM4ELMNAAPPSNCA | |
| SCHEMBL6658511 | 0.77 | KDM4E (0.42) | MAPTKDM4ELMNAAPPSNCA | |
| SCHEMBL13652077 | 0.77 | MAPT (0.73) | MAPTKDM4ELMNASNCAPOLB | |
| SCHEMBL11516456 | 0.77 | APP (0.55) | MAPTKDM4ELMNAAPPSNCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4145537-A | BENZOTHIAZOLIUM DYES | BAYER AKTIENGESELLSCHAFT (DE) | 1979-03-20 | — | — | US | disclosed |