Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.61 |
| ▸ | INSR | P06213 | 2/20 | 0.48 |
| ▸ | THRB | P10828 | 2/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | APP | P05067 | 2/20 | 0.38 |
| ▸ | SNCA | P37840 | 2/20 | 0.38 |
| ▸ | TNF | P01375 | 1/20 | 0.38 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL31063683 | 0.98 | MAPT (0.64) | MAPTKDM4EALDH1A1TDP1INSR | |
| SCHEMBL11515558 | 0.83 | MAPT (0.58) | MAPTKDM4EALDH1A1TDP1INSR | |
| Iodide SCHEMBL31063723 | 0.82 | MAPT (0.61) | MAPTKDM4EALDH1A1TDP1INSR | |
| SCHEMBL14982704 | 0.81 | MAPT (0.45) | MAPTKDM4EALDH1A1TDP1INSR | |
| Iodide SCHEMBL4013003 | 0.79 | MAPT (0.60) | MAPTKDM4EALDH1A1TDP1INSR | |
| Iodide SCHEMBL31063757 | 0.79 | MAPT (0.60) | MAPTKDM4EALDH1A1TDP1INSR | |
| SCHEMBL8032355 | 0.77 | MAPT (0.97) | MAPTKDM4EALDH1A1TDP1INSR | |
| Iodide SCHEMBL4015595 | 0.76 | MAPT (1.00) | MAPTKDM4EALDH1A1TDP1INSR | |
| SCHEMBL839316 | 0.76 | MAPT (0.52) | MAPTKDM4EALDH1A1TDP1INSR | |
| SCHEMBL30411778 | 0.76 | MAPT (0.52) | MAPTKDM4EALDH1A1TDP1INSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9850382-B1 | Unsymmetrical cyanine dyes and their application | Ying, Laiqiang (US) | 2017-12-26 | — | — | US | disclosed |
| US-8742114-B2 | Nucleic acid detections and methods of their use | Ying, Laiqiang (US) | 2014-06-03 | — | — | US | disclosed |
| US-20130137875-A1 | NUCLEIC ACID DETECTIONS AND METHODS OF THEIR USE | Ying, Laiqiang (US) | 2013-05-30 | — | — | US | disclosed |
| WO-2007090765-A2 | HIGH CAPACITY OPTICAL STORAGE MEDIA COMPRISING ORGANOMETALLIC ION PAIRS | CIBA HOLDING INC. (CH) | 2007-08-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130137875-A1 | NUCLEIC ACID DETECTIONS AND METHODS OF THEIR USE | DDB1, DNTT, DNA2 | MAPT 3684/4885KDM4E 4421/4885ALDH1A1 4104/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.