SCHEMBL11515633

SCHEMBL11515633

Cc1nc(-c2ccccc2)n(C)c1-c1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGER1 P34995 1/20 0.47
TLR7 Q9NYK1 1/20 0.46
ATM Q13315 1/20 0.46
NPC1 O15118 3/20 0.46
RAB9A P51151 3/20 0.46
ADORA3 P0DMS8 2/20 0.46
NR1H2 P55055 1/20 0.46
NR1H3 Q13133 1/20 0.46
ADORA2A P29274 2/20 0.45
ADORA2B P29275 2/20 0.45
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
DHODH Q02127 1/20 0.44
ADORA1 P30542 1/20 0.44
PI4KA P42356 1/20 0.44
PI4K2B Q8TCG2 1/20 0.44
PI4K2A Q9BTU6 1/20 0.44
PI4KB Q9UBF8 1/20 0.44
KDM4E B2RXH2 3/20 0.43
ALDH1A1 P00352 3/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL822678 0.82 PTGER1 (0.56) PTGER1TLR7ATMNPC1RAB9A
SCHEMBL5795858 0.81 ATM (0.47) TLR7ATMNPC1RAB9AADORA3
SCHEMBL27690602 0.79 ATM (0.46) TLR7ATMNPC1RAB9AADORA3
SCHEMBL719704 0.78 CYP1A2 (0.46) PTGER1TLR7ATMNPC1RAB9A
SCHEMBL9925491 0.76 AVPR1A (0.49) MEN1KMT2AADORA1PI4KAPI4K2B
SCHEMBL517706 0.73 MEN1 (0.77) TLR7ATMNPC1RAB9AMEN1
SCHEMBL8307910 0.73 KDM4E (0.47) PTGER1TLR7ATMNPC1RAB9A
SCHEMBL8307908 0.73 KDM4E (0.47) PTGER1TLR7ATMNPC1RAB9A
SCHEMBL15987599 0.73 PTGER1 (0.49) PTGER1TLR7ATMADORA2AADORA2B
SCHEMBL22219426 0.73 KMT2A (0.54) PTGER1NPC1MEN1KMT2ADHODH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4164480-A POLYMER STABILIZERS EASTMAN KODAK COMPANY (US) 1979-08-14 US disclosed
US-4105631-A MULTICHROMOPHORIC ULTRAVIOLET STABILIZERS AND THEIR USE IN ORGANIC COMPOSITIONS EASTMAN KODAK COMPANY (US) 1978-08-08 US disclosed
US-4043973-A PIGMENTS, COLORANTS, FILLERS, REINFORCING AGENTS EASTMAN KODAK COMPANY (US) 1977-08-23 US disclosed
US-3939115-A OXADIAZOLES EASTMAN KODAK COMPANY (US) 1976-02-17 US disclosed
US-3936419-A Multichromophoric ultraviolet stabilizers and their use in organic compositions EASTMAN KODAK COMPANY (US) 1976-02-03 US disclosed