SCHEMBL822678

SCHEMBL822678

Cn1c(-c2ccccc2)nc(-c2ccccc2)c1-c1ccccc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGER1 P34995 1/20 0.56
KDM4E B2RXH2 2/20 0.51
ALDH1A1 P00352 2/20 0.51
HPGD P15428 2/20 0.51
TSHR P16473 1/20 0.51
HSD17B10 Q99714 1/20 0.51
MAPK13 O15264 2/20 0.49
GCGR P47871 2/20 0.49
MAPK12 P53778 2/20 0.49
MAPK11 Q15759 2/20 0.49
MAPK14 Q16539 2/20 0.49
FABP4 P15090 2/20 0.48
FABP5 Q01469 1/20 0.48
CNR1 P21554 2/20 0.48
ALOX5 P09917 1/20 0.47
GAA P10253 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
TLR7 Q9NYK1 1/20 0.45
ATM Q13315 1/20 0.45
NPC1 O15118 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15987599 0.90 PTGER1 (0.49) PTGER1KDM4EALDH1A1HPGDTSHR
SCHEMBL27934006 0.90 PTGER1 (0.49) PTGER1KDM4EALDH1A1HPGDTSHR
SCHEMBL22219426 0.90 KMT2A (0.54) PTGER1KDM4EALDH1A1HPGDTSHR
SCHEMBL28207152 0.88 PTGER1 (0.47) PTGER1KDM4EALDH1A1HPGDTSHR
SCHEMBL27881874 0.87 LMNA (0.59) PTGER1KDM4EALDH1A1TSHRGAA
SCHEMBL11516631 0.84 KDM4E (0.51) PTGER1KDM4EALDH1A1HPGDTSHR
SCHEMBL18152791 0.84 FABP4 (0.46) PTGER1KDM4EALDH1A1HPGDTSHR
SCHEMBL11053248 0.83 ALDH1A1 (0.49) PTGER1KDM4EALDH1A1HPGDTSHR
SCHEMBL19825896 0.83 FABP4 (0.54) PTGER1KDM4EALDH1A1HPGDTSHR
SCHEMBL11515633 0.82 PTGER1 (0.47) PTGER1KDM4EALDH1A1HPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-59016879-A None JP disclosed
US-12606666-B2 Imidazoles and imidazolium cations with exceptional alkaline stability CORNELL UNIVERSITY (US) 2026-04-21 US disclosed
US-11739261-B2 Fluorescent probes for acid detection THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) 2023-08-29 US disclosed
EP-4108691-A1 IMIDAZOLIUM CATIONS WITH EXCEPTIONAL ALKALINE STABILITY Cornell University (US) 2022-12-28 EP disclosed
EP-4108691-A1 IMIDAZOLIUM CATIONS WITH EXCEPTIONAL ALKALINE STABILITY Cornell University (US) 2022-12-28 EP disclosed
EP-3283535-B1 POLYMERS COMPRISING IMIDAZOLIUM CATIONS WITH EXCEPTIONAL ALKALINE STABILITY UNIV CORNELL (US) 2022-08-10 EP disclosed
US-20220127413-A1 IMIDAZOLES AND IMIDAZOLIUM CATIONS WITH EXCEPTIONAL ALKALINE STABILITY CORNELL UNIVERSITY (US) 2022-04-28 US disclosed
US-20220127413-A1 IMIDAZOLES AND IMIDAZOLIUM CATIONS WITH EXCEPTIONAL ALKALINE STABILITY CORNELL UNIVERSITY (US) 2022-04-28 US disclosed
US-11242432-B2 Imidazoles and imidazolium cations with exceptional alkaline stability CORNELL UNIVERSITY (US) 2022-02-08 US disclosed
US-11242432-B2 Imidazoles and imidazolium cations with exceptional alkaline stability CORNELL UNIVERSITY (US) 2022-02-08 US disclosed
US-20080241740-A1 Support with photosensitive layer; reduce contact angle of water drops FUJIFILM CORPORATION (JP) 2008-10-02 US disclosed
US-20080199804-A1 Including free radical binder polymer containing functional group having dipole moment of 3.8 debye; laser computer controlled direct plate making without alkali development; sensitivity, printing durability FUJIFILM CORPORATION (JP) 2008-08-21 US disclosed
US-20080160451-A1 METHOD FOR PREPARATION OF LITHOGRAPHIC PRINTING PLATE FUJIFILM CORPORATION (JP) 2008-07-03 US disclosed
US-20080070158-A1 LITHOGRAPHIC PRINTING PLATE PRECURSOR AND METHOD FOR PREPARATION OF LITHOGRAPHIC PRINTING PLATE FUJIFILM CORPORATION (JP) 2008-03-20 US disclosed
US-20080026324-A1 LITHOGRAPHIC PRINTING PLATE PRECURSOR AND METHOD FOR PREPARATION OF LITHOGRAPHIC PRINTING PLATE FUJIFILM CORPORATION (JP) 2008-01-31 US disclosed
US-20070184387-A1 Method for preparation of lithographic printing plate and lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2007-08-09 US disclosed
US-20070128550-A1 Method for preparation of lithographic printing plate and lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2007-06-07 US disclosed
US-20070039500-A1 Manufacturing method of lithographic printing plate and manufacturing apparatus of lithographic printing plate FUJI PHOTO FILM CO., LTD. (JP) 2007-02-22 US disclosed
JP-S5916879-A PRODUCTION OF N-SUBSTITUTED IMIDAZOLE KYOWA HAKKO KOGYO CO LTD 1984-01-28 JP disclosed
EP-0010565-A1 Process for preparing N-tritylimidazole compounds SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1980-05-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220127413-A1 IMIDAZOLES AND IMIDAZOLIUM CATIONS WITH EXCEPTIONAL ALKALINE STABILITY ALPI, ITPA, ITPR2 PTGER1 4167/4885KDM4E 1492/4885ALDH1A1 1091/4885
US-11242432-B2 Imidazoles and imidazolium cations with exceptional alkaline stability ALPI, ITPA, ITPR2 PTGER1 4167/4885KDM4E 1492/4885ALDH1A1 1091/4885
US-12606666-B2 Imidazoles and imidazolium cations with exceptional alkaline stability SCO2, RCC1, SMC2 PTGER1 3806/4885KDM4E 1633/4885ALDH1A1 476/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.