Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 1/20 | 0.57 |
| ▸ | CTPS1 | P17812 | 6/20 | 0.52 |
| ▸ | MAPT | P10636 | 7/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | UBE2N | P61088 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | XBP1 | P17861 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11517104 | 0.86 | PDE5A (0.62) | PDE5ACTPS1MAPTNPSR1HTT | |
| SCHEMBL11516869 | 0.84 | PDE5A (0.62) | PDE5ACTPS1MAPTNPSR1HTT | |
| SCHEMBL11519026 | 0.84 | PDE5A (0.62) | PDE5ACTPS1MAPTNPSR1HTT | |
| SCHEMBL11516149 | 0.83 | PDE5A (0.64) | PDE5ACTPS1MAPTNPSR1HTT | |
| SCHEMBL11517733 | 0.80 | PDE5A (0.56) | PDE5ACTPS1MAPTNPSR1HTT | |
| SCHEMBL24101686 | 0.78 | PDE5A (0.63) | PDE5ACTPS1MAPTNPSR1HTT | |
| SCHEMBL14069823 | 0.78 | MAPT (0.59) | PDE5AMAPTNPSR1HTTHPGD | |
| SCHEMBL11518120 | 0.75 | MAPT (0.50) | PDE5ACTPS1MAPTNPSR1HTT | |
| SCHEMBL11516872 | 0.74 | MAPT (0.49) | PDE5ACTPS1MAPTNPSR1HTT | |
| SCHEMBL27768800 | 0.71 | SMN1; SMN2 (0.75) | MAPTNPSR1HTTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4152329-A | 2-ACYLAMINOTHIAZOL-4-YLACETAMIDES AS POST-EMERGENT SELECTIVE HERBICIDES | GULF OIL CORPORATION (US) | 1979-05-01 | — | — | US | disclosed |
| US-4120690-A | 2-Acylaminothiazol-4-ylacetamides as post-emergent selective herbicides | GULF OIL CORPORATION (US) | 1978-10-17 | — | — | US | disclosed |