Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | NOS3 | P29474 | 1/20 | 0.40 |
| ▸ | NOS1 | P29475 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4605352 | 1.00 | POLB (0.44) | POLBGAAKMT2ANPC1RAB9A | |
| SCHEMBL28358729 | 0.98 | NOS3 (0.41) | POLBGAAKMT2ANPC1RAB9A | |
| SCHEMBL23917218 | 0.88 | NOS3 (0.43) | POLBGAAKMT2ANPC1RAB9A | |
| SCHEMBL20858617 | 0.88 | NOS3 (0.43) | POLBGAAKMT2ANPC1RAB9A | |
| SCHEMBL22889 | 0.88 | NOS3 (0.43) | POLBGAAKMT2ANPC1RAB9A | |
| SCHEMBL5832697 | 0.86 | NOS3 (0.47) | POLBGAAKMT2ANPC1RAB9A | |
| SCHEMBL10427141 | 0.86 | NOS3 (0.42) | POLBGAAKMT2ANPC1RAB9A | |
| SCHEMBL1954285 | 0.86 | NOS3 (0.42) | POLBGAAKMT2ANPC1RAB9A | |
| SCHEMBL8031217 | 0.86 | NOS3 (0.42) | POLBGAAKMT2ANPC1RAB9A | |
| SCHEMBL867932 | 0.86 | NOS3 (0.42) | POLBGAAKMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4178286-A | β-Lactams, their production, intermediates thereto and derivatives thereof | RESEARCH CORPORATION (US) | 1979-12-11 | — | — | US | disclosed |