Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | NOS3 | P29474 | 1/20 | 0.40 |
| ▸ | NOS1 | P29475 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11515949 | 1.00 | POLB (0.44) | POLBGAAKMT2ANPC1RAB9A | |
| SCHEMBL28358729 | 0.98 | NOS3 (0.41) | POLBGAAKMT2ANPC1RAB9A | |
| SCHEMBL23917218 | 0.88 | NOS3 (0.43) | POLBGAAKMT2ANPC1RAB9A | |
| SCHEMBL20858617 | 0.88 | NOS3 (0.43) | POLBGAAKMT2ANPC1RAB9A | |
| SCHEMBL22889 | 0.88 | NOS3 (0.43) | POLBGAAKMT2ANPC1RAB9A | |
| SCHEMBL5832697 | 0.86 | NOS3 (0.47) | POLBGAAKMT2ANPC1RAB9A | |
| SCHEMBL10427141 | 0.86 | NOS3 (0.42) | POLBGAAKMT2ANPC1RAB9A | |
| SCHEMBL1954285 | 0.86 | NOS3 (0.42) | POLBGAAKMT2ANPC1RAB9A | |
| SCHEMBL8031217 | 0.86 | NOS3 (0.42) | POLBGAAKMT2ANPC1RAB9A | |
| SCHEMBL867932 | 0.86 | NOS3 (0.42) | POLBGAAKMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0847989-B1 | Process for producing cyclohexylazetidinone | TAKASAGO PERFUMERY CO LTD (JP) | 2002-11-13 | — | — | EP | claimed |
| US-5777103-A | CHEMICAL INTERMEDIATE FOR ANTIBIOTIC | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1998-07-07 | — | — | US | claimed |
| EP-0847989-A1 | Process for producing cyclohexylazetidinone | Takasago International Corporation (JP) | 1998-06-17 | — | — | EP | claimed |
| JP-10168057-A | — | — | None | — | — | JP | disclosed |
| CN-120065654-A | Aqueous developer composition for flexographic printing plate and method for producing flexographic printing plate | 旭化成株式会社 | 2025-05-30 | — | — | CN | disclosed |
| US-20110230457-A1 | Substituted Isoquinolinones and Quinazolinones | NOVARTIS AG (CH) | 2011-09-22 | — | — | US | disclosed |
| EP-1940853-A1 | PROCESS FOR PREPARING 1 -HYDROXY-2 -SUBSTITUTED CYCLOHEXYL AZETIDIN-2-ONE COMPOUNDS | LEK Pharmaceuticals d.d. (SI) | 2008-07-09 | — | — | EP | disclosed |
| WO-2007039099-A1 | PROCESS FOR PREPARING 1’-HYDROXY-2’-SUBSTITUTED CYCLOHEXYL AZETIDIN-2-ONE COMPOUNDS | LEK PHARMACEUTICALS D.D. (SI) | 2007-04-12 | — | — | WO | disclosed |
| EP-0847989-B1 | Process for producing cyclohexylazetidinone | TAKASAGO PERFUMERY CO LTD (JP) | 2002-11-13 | — | — | EP | disclosed |
| EP-0847989-B1 | Process for producing cyclohexylazetidinone | TAKASAGO PERFUMERY CO LTD (JP) | 2002-11-13 | — | — | EP | disclosed |
| US-5817806-A | Process for the preparation of cyclohexyl-azetidinones | GLAXO WELLCOME SPA (IT) | 1998-10-06 | — | — | US | disclosed |
| US-5777103-A | CHEMICAL INTERMEDIATE FOR ANTIBIOTIC | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1998-07-07 | — | — | US | disclosed |
| JP-H10168057-A | PRODUCTION OF CYCLOHEXYLAZETIDINONE DERIVATIVE | TAKASAGO INTERNATL CORP | 1998-06-23 | — | — | JP | disclosed |
| EP-0847989-A1 | Process for producing cyclohexylazetidinone | Takasago International Corporation (JP) | 1998-06-17 | — | — | EP | disclosed |
| EP-0847989-A1 | Process for producing cyclohexylazetidinone | Takasago International Corporation (JP) | 1998-06-17 | — | — | EP | disclosed |
| EP-0752984-A1 | PROCESS FOR THE PREPARATION OF CYCLOHEXYL-AZETIDINONES | GLAXO WELLCOME S.p.A. (IT) | 1997-01-15 | — | — | EP | disclosed |
| WO-1995026333-A1 | PROCESS FOR THE PREPARATION OF CYCLOHEXYL-AZETIDINONES | GLAXO WELLCOME S.P.A. (IT) | 1995-10-05 | — | — | WO | disclosed |
| US-4190579-A | Synthesis of beta-lactams from azetidine carboxylic acid esters | RESEARCH CORPORATION (US) | 1980-02-26 | — | — | US | disclosed |
| US-4178286-A | β-Lactams, their production, intermediates thereto and derivatives thereof | RESEARCH CORPORATION (US) | 1979-12-11 | — | — | US | disclosed |
| US-4163743-A | Beta-lactams, their production from azetidine carboxylic acids, intermediates thereto and derivatives thereof | RESEARCH CORPORATION (US) | 1979-08-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110230457-A1 | Substituted Isoquinolinones and Quinazolinones | MDM4, MDM2, TP53 | POLB 2605/4885GAA 3352/4885KMT2A 1137/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.