Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCL8 | P10145 | 8/20 | 0.58 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.47 |
| ▸ | TTR | P02766 | 2/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.47 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.47 |
| ▸ | UGT1A9 | O60656 | 1/20 | 0.47 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.47 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.47 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.47 |
| ▸ | ALB | P02768 | 1/20 | 0.47 |
| ▸ | UGT1A6 | P19224 | 1/20 | 0.47 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.47 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.47 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.47 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.47 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11515988 | 0.88 | CXCL8 (0.62) | CXCL8CASP1PTGS2TTRPTGS1 | |
| SCHEMBL4632797 | 0.81 | CASP1 (0.70) | CASP1ALDH1A1KMT2ATSHRHIF1A | |
| SCHEMBL4632799 | 0.81 | CASP1 (0.70) | CASP1ALDH1A1KMT2ATSHRHIF1A | |
| SCHEMBL11435906 | 0.80 | CXCL8 (0.71) | CXCL8PTGS2TTRPTGS1AKR1B10 | |
| SCHEMBL576512 | 0.78 | CXCL8 (0.50) | CXCL8CASP1METTL3PTGS2TTR | |
| SCHEMBL11516585 | 0.78 | CXCL8 (0.59) | CXCL8PTGS2TTRPTGS1AKR1B10 | |
| SCHEMBL16797728 | 0.77 | CASP1 (0.54) | CASP1ALDH1A1LMNAMAPK1KMT2A | |
| SCHEMBL577228 | 0.77 | CXCL8 (0.45) | CXCL8METTL3PTGS2TTRPTGS1 | |
| SCHEMBL13186033 | 0.76 | CXCL8 (0.68) | CXCL8PTGS2TTRPTGS1AKR1B10 | |
| SCHEMBL28809681 | 0.75 | CXCL8 (0.71) | CXCL8METTL3PTGS2TTRPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4166128-A | ANALGESICS, ANTIINFLAMMATORY AGENTS, ANTIPYRETICS, ANTIARTHRITIC AGENTS, RHEUMATIC DISEASES | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1979-08-28 | — | — | US | disclosed |