Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | TLR2 | O60603 | 1/20 | 0.39 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Zafuleptine SCHEMBL2110004 | 0.89 | HTT (0.48) | HPGDLMNAHDAC3HDAC1HDAC2 | |
| SCHEMBL11519292 | 0.89 | HTT (0.48) | HPGDLMNAHDAC3HDAC1HDAC2 | |
| SCHEMBL11516002 | 0.89 | HTT (0.48) | HPGDLMNAHDAC3HDAC1HDAC2 | |
| SCHEMBL11519593 | 0.88 | HTT (0.49) | HPGDLMNAHDAC3HDAC1HDAC2 | |
| SCHEMBL11515245 | 0.85 | LMNA (0.49) | HPGDLMNAHDAC3HDAC1HDAC2 | |
| SCHEMBL11516756 | 0.84 | HPGD (0.42) | HPGDLMNAHDAC3HDAC1HDAC2 | |
| SCHEMBL11520085 | 0.83 | MEN1 (0.43) | HPGDLMNAMAPK1TSHRMEN1 | |
| SCHEMBL11518505 | 0.82 | MAPK1 (0.49) | HPGDLMNAMAPK1TSHRMEN1 | |
| SCHEMBL11519570 | 0.78 | HDAC1 (0.40) | HPGDLMNAHDAC3HDAC1HDAC2 | |
| SCHEMBL11520175 | 0.78 | TAAR1 (0.51) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4154851-A | ANTIDEPRESSANTS, ANTIAGRESSIVE AGENTS | SCIENCE UNION ET CIE, SOCIETE FRANCAISE DE RECHERCHE MEDICALE (FR) | 1979-05-15 | — | — | US | disclosed |