Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.51 |
| ▸ | FKBP1A | P62942 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | NAAA | Q02083 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11516874 | 0.81 | CTSS (0.44) | FKBP1AALDH1A1KMT2AMEN1CTSS | |
| SCHEMBL11519593 | 0.79 | HTT (0.49) | KMT2AMEN1 | |
| Zafuleptine SCHEMBL2110004 | 0.78 | HTT (0.48) | KMT2AMEN1 | |
| SCHEMBL11516163 | 0.78 | HPGD (0.43) | KMT2AMEN1 | |
| SCHEMBL11516002 | 0.78 | HTT (0.48) | KMT2AMEN1 | |
| SCHEMBL11519292 | 0.78 | HTT (0.48) | KMT2AMEN1 | |
| SCHEMBL11515245 | 0.77 | LMNA (0.49) | KMT2AMEN1 | |
| SCHEMBL9557074 | 0.76 | TAAR1 (0.68) | TAAR1FKBP1ANPC1ALDH1A1KMT2A | |
| SCHEMBL11516756 | 0.76 | HPGD (0.42) | KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL11520085 | 0.75 | MEN1 (0.43) | KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4154851-A | ANTIDEPRESSANTS, ANTIAGRESSIVE AGENTS | SCIENCE UNION ET CIE, SOCIETE FRANCAISE DE RECHERCHE MEDICALE (FR) | 1979-05-15 | — | — | US | disclosed |