Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | INSR | P06213 | 5/20 | 0.60 |
| ▸ | APP | P05067 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.54 |
| ▸ | MAPT | P10636 | 8/20 | 0.54 |
| ▸ | HTT | P42858 | 7/20 | 0.54 |
| ▸ | MEN1 | O00255 | 7/20 | 0.54 |
| ▸ | THRB | P10828 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | MMP14 | P50281 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 7/20 | 0.53 |
| ▸ | RAB9A | P51151 | 7/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | PKM | P14618 | 2/20 | 0.53 |
| ▸ | NSD2 | O96028 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.52 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11516285 | 1.00 | INSR (0.60) | INSRAPPKMT2AMAPTHTT | |
| SCHEMBL12611251 | 0.81 | INSR (0.63) | INSRAPPKMT2AMAPTHTT | |
| Hydrochloric Acid SCHEMBL11516462 | 0.80 | INSR (0.67) | INSRAPPKMT2AMAPTHTT | |
| Hydrochloric Acid SCHEMBL11516460 | 0.80 | INSR (0.67) | INSRAPPKMT2AMAPTHTT | |
| Hydrochloric Acid SCHEMBL11515680 | 0.78 | INSR (0.66) | INSRAPPKMT2AMAPTHTT | |
| Hydrochloric Acid SCHEMBL11516278 | 0.78 | INSR (0.49) | INSRAPPKMT2AMAPTHTT | |
| Hydrochloric Acid SCHEMBL11516276 | 0.78 | INSR (0.49) | INSRAPPKMT2AMAPTHTT | |
| Hydrochloric Acid SCHEMBL11515678 | 0.78 | INSR (0.66) | INSRAPPKMT2AMAPTHTT | |
| SCHEMBL16800102 | 0.78 | MAPT (0.63) | INSRAPPKMT2AMAPTHTT | |
| SCHEMBL17322556 | 0.76 | INSR (0.75) | INSRAPPKMT2AMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4145537-A | BENZOTHIAZOLIUM DYES | BAYER AKTIENGESELLSCHAFT (DE) | 1979-03-20 | — | — | US | disclosed |