Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.63 |
| ▸ | HTT | P42858 | 7/20 | 0.63 |
| ▸ | MEN1 | O00255 | 7/20 | 0.63 |
| ▸ | LMNA | P02545 | 4/20 | 0.63 |
| ▸ | THRB | P10828 | 3/20 | 0.63 |
| ▸ | MMP14 | P50281 | 1/20 | 0.63 |
| ▸ | INSR | P06213 | 1/20 | 0.62 |
| ▸ | APP | P05067 | 2/20 | 0.59 |
| ▸ | RAB9A | P51151 | 8/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.55 |
| ▸ | NPC1 | O15118 | 7/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.55 |
| ▸ | GAA | P10253 | 3/20 | 0.55 |
| ▸ | POLB | P06746 | 3/20 | 0.55 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.55 |
| ▸ | RAD52 | P43351 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | PKM | P14618 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17322556 | 0.84 | INSR (0.75) | MAPTKMT2AHTTMEN1LMNA | |
| SCHEMBL12439978 | 0.81 | MAPT (0.61) | MAPTKMT2AHTTMEN1LMNA | |
| SCHEMBL16791401 | 0.81 | MAPT (0.57) | MAPTKMT2AHTTMEN1LMNA | |
| SCHEMBL13005216 | 0.79 | INSR (0.57) | MAPTKMT2AHTTMEN1LMNA | |
| SCHEMBL13672949 | 0.79 | MAPT (0.97) | MAPTKMT2AHTTMEN1LMNA | |
| SCHEMBL34468132 | 0.79 | INSR (0.72) | MAPTKMT2AHTTMEN1LMNA | |
| SCHEMBL14561804 | 0.79 | ADRB2 (0.61) | MAPTKMT2AHTTMEN1LMNA | |
| SCHEMBL16800095 | 0.79 | ADRB2 (0.61) | MAPTKMT2AHTTMEN1LMNA | |
| Iodide SCHEMBL12470899 | 0.78 | INSR (0.70) | MAPTKMT2AHTTMEN1LMNA | |
| SCHEMBL11516289 | 0.78 | INSR (0.60) | MAPTKMT2AHTTMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160299078-A1 | Specific Detection and Quantification of Cardiolipin and Isolated Mitochondria by Positively Charged AIE Fluorogens and Method of Manufacturing Thereof | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2016-10-13 | — | — | US | disclosed |
| US-20160299078-A1 | Specific Detection and Quantification of Cardiolipin and Isolated Mitochondria by Positively Charged AIE Fluorogens and Method of Manufacturing Thereof | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2016-10-13 | — | — | US | disclosed |
| WO-2015081860-A1 | SPECIFIC DETECTION AND QUANTIFICATION OF CARDIOLIPIN AND ISOLATED MITOCHONDRIA BY POSITIVELY CHARGED AIE FLUOROGENS AND METHOD OF MANUFACTURING THEREOF | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2015-06-11 | — | — | WO | disclosed |