Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | PRKCI | P41743 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | GFER | P55789 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 8/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL526857 | 0.80 | ALDH1A1 (0.48) | PDE10AALDH1A1PRKCICASP1TSHR | |
| SCHEMBL23864872 | 0.80 | TDP1 (0.41) | ALDH1A1TDP1MAPTKDM4EMEN1 | |
| SCHEMBL9329755 | 0.79 | PRKCI (0.49) | ALDH1A1PRKCICASP1TSHRACHE | |
| SCHEMBL10887495 | 0.78 | PRKCI (0.43) | PDE10AALDH1A1PRKCICASP1TSHR | |
| SCHEMBL6515925 | 0.78 | CYP3A4 (0.41) | ALDH1A1TSHRACHECYP3A4RECQL | |
| Hydrochloric Acid SCHEMBL9820908 | 0.78 | ALDH1A1 (0.47) | PDE10AALDH1A1PRKCICASP1TSHR | |
| Hydrochloric Acid SCHEMBL3336490 | 0.78 | ALDH1A1 (0.47) | PDE10AALDH1A1PRKCICASP1TSHR | |
| Hydrochloric Acid SCHEMBL30338656 | 0.78 | ALDH1A1 (0.47) | PDE10AALDH1A1PRKCICASP1TSHR | |
| Hydrochloric Acid SCHEMBL7079849 | 0.77 | ALDH1A1 (0.45) | PDE10AALDH1A1PRKCICASP1TSHR | |
| SCHEMBL21991015 | 0.77 | ALDH1A1 (0.45) | PDE10AALDH1A1PRKCICASP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101229106-B | Dye composition of acidic ph comprising 2,3-diamino-6,7-dihydro-1h,5h-pyrazolo[1,2-a]pyrazol-1-one, a para- phenylenediamine, a meta-aminophenol and an oxidizing agent | OREAL | 2013-04-10 | — | — | CN | claimed |
| EP-0370880-A1 | Trialkoxy-substituted m-phenylene diamines, process for their preparation, and their use as coupling agents in the oxidation dyeing of keratinic fibres, especially human hair | L'OREAL (FR) | 1990-05-30 | — | — | EP | claimed |
| CN-107223124-B | The compound for carrying the azomethine type of Pyrazolopyridine unit is used for the purposes of dyeing keratin fibres | 欧莱雅 | 2019-10-25 | — | — | CN | disclosed |
| CN-109310607-A | The compound for carrying the azomethine type of quinoline derivatives unit is used for the purposes of dyeing keratin fibres | 莱雅公司 | 2019-02-05 | — | — | CN | disclosed |
| CN-109311879-A | Symmetrical (asymmetry) azomethine type direct dyes comprising at least one Pyrazolopyridine unit, the method for using the dyeing keratin fiber | 莱雅公司 | 2019-02-05 | — | — | CN | disclosed |
| CN-107049807-A | For dyeing keratinous fibres and/or the double reagent of bleaching | 欧莱雅 | 2017-08-18 | — | — | CN | disclosed |
| CN-106456491-A | Process for bleaching or dyeing keratin fibres using an oxidizing composition and UV-visible radiation | 欧莱雅 | 2017-02-22 | — | — | CN | disclosed |
| CN-103998417-B | Specific quinone direct dyes, comprise the dye composite of at least one this dyestuff, its implementation and application thereof | 欧莱雅 | 2016-10-19 | — | — | CN | disclosed |
| EP-2771070-A1 | DEVICE FOR SELF-FOAMING OXIDATION DYEING, READY-FOR-USE SELF-FOAMING COMPOSITION AND METHOD FOR DYEING KERATINOUS FIBRES | L'Oréal (FR) | 2014-09-03 | — | — | EP | disclosed |
| CN-103998015-A | Cationic tetrahydropyrazolopyridines, dye composition comprising such oxidation bases, implementation process therefor and use thereof | OREAL | 2014-08-20 | — | — | CN | disclosed |
| CN-103764111-A | Dye composition comprising cationic para-aminophenol oxidation base | OREAL | 2014-04-30 | — | — | CN | disclosed |
| CN-1277528-C | Dyeing compson. for kerationous fibres comprising particular dicationic diazo dye | OREAL (FR) | 2006-10-04 | — | — | CN | disclosed |
| CN-1245938-C | Novel dyeing composition for dyeing-keratinous fibers comprising particular dicationic diazo dye | OREAL (FR) | 2006-03-22 | — | — | CN | disclosed |
| CN-1596098-A | Dyeing composition comprising a diaminopyrazole-type oxidation base a heterocyclic oxidation base and a coupling agent | OREAL (FR) | 2005-03-16 | — | — | CN | disclosed |
| CN-1541207-A | Dyeing compsn. for kerationous fibres comprising particular dicationic diazo dye | �ź㴫 | 2004-10-27 | — | — | CN | disclosed |
| CN-1512874-A | Novel dyeing composition for dyeing-keratinous fibers comprising particular dicationic diazo dye | �ź㴫 | 2004-07-14 | — | — | CN | disclosed |
| EP-1372585-A1 | OXIDATION DYEING COMPOSITION 3-AMINO PYRAZOLO- 1,5-A]-PYRIDINE AND ONE PYRAZOLOTRIAZOLE COUPLING AGENT | L'OREAL (FR) | 2004-01-02 | — | — | EP | disclosed |
| EP-1372582-A1 | OXIDATION DYEING COMPOSITION CONTAINING 3-AMINO PYRAZOLO- 1,5-A] PYRIDINE AND 2-AMINO-3-HYDROXY PYRIDINE | L'OREAL (FR) | 2004-01-02 | — | — | EP | disclosed |
| WO-2002076418-A1 | OXIDATION DYEING COMPOSITION 3-AMINO PYRAZOLO-[1,5-A]-PYRIDINE AND ONE PYRAZOLOTRIAZOLE COUPLING AGENT | L'OREAL (FR) | 2002-10-03 | — | — | WO | disclosed |
| WO-2002076416-A1 | OXIDATION DYEING COMPOSITION CONTAINING 3-AMINO PYRAZOLO-[1,5-A] PYRIDINE AND 2-AMINO-3-HYDROXY PYRIDINE | L'OREAL (FR) | 2002-10-03 | — | — | WO | disclosed |